Investigations
|
PAH
|
Non-PH
|
P
value
|
---|
(n = 27)
|
(n = 34)
|
---|
Mean ± SD or n (%)
|
Mean ± SD or n (%)
|
---|
TTE parameters
| | | |
RA area, cm
2
| 20.8 ± 6.6 | 17.6 ± 4.2 | 0.038 |
TRV, m/s
| 3.4 ± 0.6 | 2.7 ± 0.9 | 0.0002 |
sPAP, mm Hg
| 57.7 ± 19.6 | 41.6 ± 10.6 | 0.0004 |
RAD
a
on ECG
| 3 (13) | 3 (12) | 0.073 |
PFT results
| | | |
FVC, % pred
| 91.6 ± 15.1 | 90.9 ± 25.6 | 0.900 |
DLCO
b
, % pred
| 47.9 ± 11.7 | 60.6 ± 14.9 | 0.0008 |
FVC/DLCO
| 2.0 ± 0.5 | 1.6 ± 0.4 | 0.0003 |
RHC results
| | | |
mPAP, mm Hg
| 36.4 ± 10.1 | 19.4 ± 3.4 | <0.0001 |
mRAP, mm Hg
| 9.7 ± 3.9 | 5.5 ± 2.9 | 0.0001 |
PVR, Wood units
| 5.7 ± 3.3 | 1.9 ± 0.9 | <0.0001 |
-
aRight axis deviation (RAD) defined as QRS axis of at least 90°. bDiffusing capacity for carbon monoxide (DLCO) values are reported as percentage predicted values, corrected for hemoglobin. ECG, electrocardiogram; FVC, forced vital capacity (percentage predicted); mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; PAH, pulmonary arterial hypertension; PFT, pulmonary function test; PH, pulmonary hypertension; pred, predictive value; PVR, pulmonary vascular resistance; RA, right atrium; RHC, right heart catheterization; SD, standard deviation; sPAP, systolic pulmonary artery; TRV, tricuspid regurgitant velocity; TTE, transthoracic echocardiography.