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Table 2 Comparison of cardiac and pulmonary investigation parameters in pulmonary arterial hypertension and non-pulmonary hypertension groups

From: A comparison of the predictive accuracy of three screening models for pulmonary arterial hypertension in systemic sclerosis

Investigations

PAH

Non-PH

P value

(n = 27)

(n = 34)

Mean ± SD or n (%)

Mean ± SD or n (%)

TTE parameters

   

   RA area, cm 2

20.8 ± 6.6

17.6 ± 4.2

0.038

   TRV, m/s

3.4 ± 0.6

2.7 ± 0.9

0.0002

   sPAP, mm Hg

57.7 ± 19.6

41.6 ± 10.6

0.0004

RAD a on ECG

3 (13)

3 (12)

0.073

PFT results

   

   FVC, % pred

91.6 ± 15.1

90.9 ± 25.6

0.900

   DLCO b , % pred

47.9 ± 11.7

60.6 ± 14.9

0.0008

   FVC/DLCO

2.0 ± 0.5

1.6 ± 0.4

0.0003

RHC results

   

   mPAP, mm Hg

36.4 ± 10.1

19.4 ± 3.4

<0.0001

   mRAP, mm Hg

9.7 ± 3.9

5.5 ± 2.9

0.0001

   PVR, Wood units

5.7 ± 3.3

1.9 ± 0.9

<0.0001

  1. aRight axis deviation (RAD) defined as QRS axis of at least 90°. bDiffusing capacity for carbon monoxide (DLCO) values are reported as percentage predicted values, corrected for hemoglobin. ECG, electrocardiogram; FVC, forced vital capacity (percentage predicted); mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; PAH, pulmonary arterial hypertension; PFT, pulmonary function test; PH, pulmonary hypertension; pred, predictive value; PVR, pulmonary vascular resistance; RA, right atrium; RHC, right heart catheterization; SD, standard deviation; sPAP, systolic pulmonary artery; TRV, tricuspid regurgitant velocity; TTE, transthoracic echocardiography.