Table 3 Comparison of the performance of DETECT versus ESC/ERS versus ASIG screening models for pulmonary arterial hypertension in patients with systemic sclerosis
PAH prevalence set at 10% a | ||||||
|---|---|---|---|---|---|---|
DETECT | ESC/ERS | ASIG | DETECT | ESC/ERS | ASIG | |
n = 61 | n = 58 | n = 37 | n = 61 | n = 58 | n = 37 | |
Positive b | 49 (80.3) | 48 (82.8) | 25 (67.6) | |||
Negative b | 12 (19.7) | 10 (17.2) | 12 (32.4) | |||
True PAH on RHC c | 27 (44.3) | 27 (46.55) | 15 (40.54) | |||
Sensitivity | 100% | 96.3% | 100% | 100% | 96.3% | 100% |
(95% CI) | (87.2-100) | (81.0-99.9) | (78.2-100) | (54.1-100) | (54.1-100) | (39.8-100) |
Specificity | 35.3% | 32.3% | 54.5% | 35.3% | 32.3% | 54.5% |
(95% CI) | (19.7-53.5) | (16.7-51.4) | (32.2-75.6) | (23.8-50.4) | (15.6-41.0) | (33.5-69.2) |
PPV | 55.1% | 55.3% | 60% | 14.7% | 13.6% | 19.6% |
(95% CI) | (40.2-69.3) | (40.1-69.8) | (38.7-78.8) | (5.6-29.2) | (5.2-27.4) | (5.7-43.7) |
NPV | 100% | 90.9% | 100% | 100% | 98.7% | 100% |
(95% CI) | (63.1-100) | (58.7-99.8) | (73.5-100) | (83.2-100) | (76.8-100) | (80.5-100) |