Table 1 Citrullinated (cit) and homocitrullinated (Hcit) vimentin peptides identified in human tissue samples
Vimentin peptides | Frequency of detection | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lung | Lymph node | Liver | Kidney | Spleen | Ovary | Heart | Skeletal muscle | |||||
COPD smokers | COPD ex-smokers | Never smokers | Smokers without COPD | |||||||||
Citrullinated | 70 L(cit)SSVPGVR78 / 71(cit)SSVPGVR78 | 2/4 | 1/2 | 2/3 | 2/3 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 |
295FADLSEAAN(cit)NNDALR310 | 0/4 | 0/2 | 1/3 | 0/3 | 0/1 | 0/1 | 1/1 | 1/1 | 1/1 | 0/1 | 0/1 | |
344QM(cit)EMEENFAVEAANYQDTIGR365 | 0/4 | 0/2 | 1/3 | 0/3 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | |
403LLEGEES(cit)ISLPLPNFSSLNLR424 | 1/4 | 0/2 | 1/3 | 1/3 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | |
446TVET(cit)DGQVINETSQHHDDLE466 | 1/4 | 0/2 | 2/3 | 2/3 | 1/1 | 0/1 | 1/1 | 0/1 | 1/1 | 0/1 | 0/1 | |
Homocitrullinated | 101TNE(Hcit)VELQELNDRFANYIDKVR122 | 2/4 | 2/2 | 1/3 | 0/3 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 |