Skip to main content

Table 1 Dominant metabolic pathways in resting and activated T cells

From: T-cell metabolism in autoimmune disease

Metabolic pathway Naïve resting cells Effector cells Memory cells
Glycolysis + +++ +
Pentose phosphate pathway + +++ ?
Tricarboxylic acid cycle ++ ++ +++
Oxidative phosphorylation ++ + ++
Glutaminolysis + +++ ?
Fatty acid oxidation ++ −/+ ++
  1. +, Mild activity; ++, high activity; +++, intensive activity; −/+, context-dependent activity; ?, unknown.