Figure 2From: Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice Epiphyseal trabecular bone volume fraction (BV/TV; left column), trabecular thickness (Tb.Th; center column), and subchondral cortical bone thickness (C.Th; right column) at the distal femur at each time point. High-dose alendronate (ALN-H) treatment was able to preserve trabecular bone volume and trabecular thickness at all time points, and inhibit sclerosis of the subchondral cortical bone at day 56. ALN-L, low-dose alendronate; VEH, vehicle.Back to article page