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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Circulating miRNAs as potential biomarkers of therapy effectiveness in rheumatoid arthritis patients treated with anti-TNFα

Figure 4

Changes in serum miRNAs correlate with changes in clinical variables in RA patients. Changes after anti-TNFα/DMARDs combination therapy (T1-T2) of various miRNAs significantly correlated with the changes in DAS28 (A-C), in CRP (D-E) and in ESR (F). r values of Spearman’s rank correlation and P values of their null hypothesis are shown. CRP, C-reactive protein; DAS28, disease activity score; DMARDs, disease-modifying antirheumatic drugs; ESR, erythrocyte sedimentation rate; miRNAs, microRNAs; RA, rheumatoid arthritis; T1, baseline; T2, at 6 months; TNFα, tumor necrosis factor alpha.

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