Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 3 Univariate and multivariate association of traditionalcardiovascular risk factors and RA-rated factors with severe subclinical atherosclerosis

From: Significant effects of biologic therapy on lipid profiles and insulin resistance in patients with rheumatoid arthritis

Risk factors (univariate) Odds ratio 95% confidence interval P value
Age 1.09 1.04-1.14 0.000
Sex (female) 0.89 0.18-4.39 0.883
Smoking status 3.87 0.79-19.06 0.096
Hypertension Rx. 1.35 0.55-3.32 0.517
Body mass index 0.95 0.86-1.05 0.328
Total cholesterol 1.00 0.98-1.01 0.491
HDL-C 1.01 0.98-1.04 0.467
LDL-C 1.00 0.98-1.01 0.511
Total triglyceride 1.00 0.99-1.02 0.640
Artherogenic index 2.12 1.05-4.25 0.035
Modified FRS 1.20 1.01-1.42 0.033
Insulin resistance 2.43 1.50-3.93 0.000
Disease duration >10 years 3.33 1.36-8.15 0.008
RF positivity 1.41 0.44-4.44 0.562
Anti-CCP positivity 1.44 0.89-2.35 0.142
TNF-α levels 1.00 0.99-1.00 0.743
IL-6 levels 1.00 1.00-1.00 0.196
DAS28 2.94 1.58-5.49 0.001
Risk factors (multivariate) Odds ratio 95% confidence interval P value
Age 1.08 1.02-1.15 0.007
Artherogenic index 1.31 0.98-1.76 0.073
Modified FRS 1.17 0.97-1.40 0.093
Insulin resistance 2.77 1.40-5.46 0.003
Disease duration >10 years 5.89 0.93-37.16 0.059
DAS28 2.52 1.00-6.35 0.049
  1. Anti-CCP, anti-cyclic citrullinated peptide (antibodies); DAS28, disease activity score for 28-joints; FRS, Framingham risk score; HDL-C, high-density lipoprotein cholesterol; IL-6, interleukin-6; LDL-C, low-density lipoprotein cholesterol; RF, rheumatoid factor; Rx, treatment; TNF-α, tumor necrosis factor-alpha.