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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early rheumatoid arthritis: an observational study

Figure 3

Quantitative power Doppler area (PQuant) and synovial thickness quantitative area (SQuant) correlate with angiogenic and lymphangiogenic factors. Graphical representation of relationship of PQuant and SQuant (measured in pixels) with vascular endothelial growth factor (VEGF)α, Angiopoietin 2, IL-1β and VEGF-R3. Regression line and 95% CI shown in each graph. (A) Correlation between PQuant and VEGFa on the y-axis (Spearman r = 0.52). (B) PQuant correlated with Angiopoietin 2 (Spearman r = 0.61). (C) PQuant correlated with IL-1β (Spearman r = 0.68). (D) PQuant correlated with VEGF-R3 (Spearman r = 0.61). (E) SQuant correlated with VEGFα on the y-axis (Spearman r = 0.56). (F) SQuant correlated with Angiopoietin 2, (Spearman r = 0.74). (G) SQuant correlated with IL-1β (Spearman r = 0.81). (H) SQuant correlated with VEGF-R3 (Spearman r = 0.61).

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