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Table 2 Clinical features at baseline and last follow-up visit in patients in the high and low pulse-wave velocity (PWV) groups

From: Cumulative inflammatory burden is independently associated with increased arterial stiffness in patients with psoriatic arthritis: a prospective study

 

Baseline

Last visit

 

Low PWV

High PWV

P -value

Low PWV

High PWV

P -value

Male gender, n (%)

17 (50.0%)

19 (50.0%)

1.000

17 (50.0%)

19 (50.0%)

1.000

Age, years

43.3 ± 10.2

55.2 ± 10.0

<0.001

49.6 ± 10.1

61.6 ± 9.9

<0.001

Psoriatic arthritis (PsA) characteristics

      

  PsA disease duration, years

7.6 ± 7.0

10.7 ± 7.5

0.073

13.9 ± 7.2

17.1 ± 7.8

0.075

  Tender joint count, 0 to 68

2 (0 to 6)

3 (0 to 8)

0.551

1 (0 to 3)

1 (0 to 5)

0.248

  Swollen joint count, 0 to 66

0 (0 to 2)

1 (0 to 3)

0.827

0 (0 to 1)

0 (0 to 1)

0.376

  Damaged joint count, 0 to 68

1 (0 to 3)

2 (0 to 6)

0.118

0 (0 to 4)

4 (0 to 8)

0.010

  Visual analog scale pain, 0 to 100

40 (20 to 60)

50 (30 to 70)

0.212

30 (20 to 50)

30 (20 to 60)

0.964

  Patients’ global assessment, 0 to 100

50 (20 to 60)

50 (40 to 60)

0.258

50 (20 to 60)

33 (20 to 60)

0.654

  Physicians’ global assessment, 0 to 100

10 (0 to 20)

20 (5 to 30)

0.462

19 (6 to 35)

20 (7 to 30)

0.399

  Psoriasis Area and Severity Index, 0 to 72

2.6 (1.0 to 7.3)

3.0 (0.7 to 7.7)

0.879

1.8 (0.6 to 5.4)

1.7 (0.3 to 7.4)

0.879

  Health assessment questionnaire, 0 to 3

0.25 (0.13 to 0.63)

0.56 (0.13 to 1.00)

0.120

0.13 (0 to 0.50)

0.38 (0 to 1.13)

0.146

  Minimal disease activity, n (%)

10 (29.4%)

6 (15.8%)

0.165

6 (17.6%)

8 (21.1%)

0.715

  Disease Activity in Psoriatic Arthritis, 0 to 164

14 (7 to 19)

17 (12 to 22)

0.132

11 (7 to 15)

12 (5 to 18)

0.827

  Erythrocyte sedimentation rate, mm/1st h

16 (7 to 34)

27 (13 to 56)

0.048

11 (5 to 22)

29 (13 to 56)

<0.001

  C-reactive protein, mg/dl

0.3 (0.1 to 1.2)

0.5 (0.2 to 1.3)

0.527

0.2 (0.1 to 0.5)

0.4 (0.2 to 0.8)

0.023

Cardiovascular risk factors

      

  Body weight, kg

66.1 ± 12.4

64.4 ± 11.8

0.540

68.1 ± 12.0

63.6 ± 11.0

0.099

  Body height, cm

161 ± 8

161 ± 9

0.891

   

  Systolic blood pressure, mmHg

132 ± 23

140 ± 21

0.113

121 ± 13

132 ± 16

0.002

  Hypertension, n (%)

10 (29.4%)

26 (68.4%)

0.001

15 (44.1%)

29 (76.3%)

0.005

  Diabetes, n (%)

3 (8.8%)

13 (34.2%)

0.010

3 (8.8%)

13 (34.2%)

0.010

  Framingham 10-year CVD risk >10%, n (%)

8 (23.5%)

22 (57.9%)

0.003

9 (26.5%)

27 (71.1%)

<0.001

  Total cholesterol, mmol/L

5.1 ± 0.9

5.1 ± 1.0

0.814

5.0 ± 1.0

4.8 ± 0.7

0.468

  High-density lipoprotein cholesterol, mmol/L

1.6 ± 0.5

1.6 ± 0.5

0.782

1.5 ± 0.4

1.4 ± 0.4

0.467

  Triglycerides, mmol/L

1.4 ± 0.7

1.6 ± 1.1

0.285

1.3 ± 0.8

1.5 ± 1.0

0.363

  Fasting glucose, mmol/L

5.3 ± 1.6

5.7 ± 1.0

0.227

5.2 ± 1.0

5.6 ± 1.9

0.287

Medications, n (%)

      

  Anti-hypertensive drugs

3 (8.8%)

17 (44.7%)

<0.001

14 (41.2%)

28 (73.7%)

0.005

  Statins

0 (0%)

1 (2.6%)

1.000

7 (20.6%)

7 (18.4%)

0.817

  Nonsteroidal anti-inflammatory drugs

13 (38.2%)

20 (52.6%)

0.221

16 (47.1%)

15 (39.5%)

0.516

  Steroids

2 (5.9%)

2 (5.3%)

0.999

1 (2.9%)

2 (5.3%)

0.999

  Disease-modifying antirheumatic drugs

15 (44.1%)

21 (55.3%)

0.345

18 (52.9%)

22 (57.9%)

0.673

  Biologics

0 (0%)

0 (0%)

N.S.

7 (20.6%)

4 (10.5%)

0.236

  1. Variables with P-values <0.1 (values in bold text) were candidates for multivariate analysis. Values are presented as number (percentage), median (interquatile range), or mean ± SD.