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Table 1 Characteristics of the study sample for association analyses

From: CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women

Variable

Rheumatoid arthritis cases

Rheumatoid arthritis-free controls

(n = 521)

(n = 321)

Sex, % female (n)

83.3 (434)

72.0 (231)*

Age at inclusion, years (range)

51.6 ± 11.2 (19 to 80)

39.4 ± 15.1 (18 to 78)*

Age of onset, years (range)

40.7 ± 12.8 (2 to 75)

NA

Duration of disease, years (range)

10.8 ± 8.3 (1 to 45)

NA

Rheumatoid factor, IU/mla

149.8 ± 67.2

ND

Rheumatoid factor-positive, % (n)

55.0 (279)

ND.

Anti-CCP antibody, RU/mlb

67.5 ± 53.7

ND

Anti-CCP positive, % (n)c

78.6 (239)

ND

C-reactive protein, mg/l

19.6 ± 23.7

ND

  1. Values denote mean ± standard deviation unless indicated otherwise. *Significant (P <0.001); arheumatoid factor serum levels were determined in 507 rheumatoid arthritis cases; banti-CCP antibody serum levels were determined in n = 304 RA patients; cvalues <4.2 RU/ml were considered as anti-CCP negative. NA, not applicable; ND, not determined; anti-CCP: antibody against cyclic citrullinated peptide specific for rheumatoid arthritis.