CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women

Table 3 CYB5A single nucleotide polymorphism (SNP) association analysis results in a rheumatoid arthritis (RA) case-control replication sample of Slovak patients and controls

	RA case genotypes					RA-free control genotypes					Association results
SNP	11	12	22	MAF	P (HWE)	11	12	22	MAF	P (HWE)	P ^a	Odds ratio for minor allele (95% CI) ^a
rs1790858	510	11	0	0.011	1	313	8	0	0.012	1	0.835	0.91 (0.36, 2.30)
rs1790834	388	122	11	0.138	0.71	187	95	7	0.189	0.25	8.5*10⁻³	0.69 (0.52, -0.91)

^aLogistic regression adjusted for sex. Numbers of genotypes according to alleles from Table 2. MAF, minor allele frequency; HWE, Hardy-Weinberg equilibrium.

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