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Table 4 Conditional logistic regression analysis a

From: Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus

  

SNP whose effect is adjusted for

  

rs463426

rs131654

rs2266959

rs181359

rs5754217

rs2298428

rs463426

OR (95% CI)

 

1.14 (1.01 to 1.27)

1.02 (0.91 to 1.14)

1.1 (0.98 to 1.23)

1.09 (0.98 to 1.23)

1.05 (0.94 to 1.17)

P-value

0.03

0.74

0.12

0.12

0.39

rs131654

OR (95% CI)

1.10 (0.98 to 1.24)

 

0.95 (0.82 to 1.10)

0.99 (0.81 to 1.21)

0.94 (0.77 to 1.15)

0.96 (0.85 to 1.10)

P-value

0.09

0.51

0.92

0.57

0.59

rs2266959

OR (95% CI)

1.27 (1.14 to 1.43)

1.33 (1.16 to 1.53)

 

1.37 (1.15 to 1.63)

1.36 (1.14 to 1.62)

0.79 (0.43 to 1.45)

P-value

3.02E-05

4.36E-05

4.69E-04

5.21E-04

0.44

rs181359

OR (95% CI)

1.16 (1.04 to 1.30)

1.25 (1.03 to 1.52)

0.92 (0.77 to 1.11)

 

0.17 (0.01 to 3.89)

0.98 (0.83 to 1.14)

P-value

8.88E-03

0.02

0.39

0.27

0.76

rs5754217

OR (95% CI)

1.17 (1.04 to 1.31)

1.3 (1.08 to 1.57)

0.93 (0.77 to 1.11)

0.94 (0.77 to 1.11)

 

0.98 (0.84 to 1.14)

P-value

7.21E-03

6.75E-03

0.41

0.20

0.79

rs2298428

OR (95% CI)

1.27 (1.14 to 1.41)

1.33 (1.18 to 1.51)

1.61 (0.87 to 2.95)

1.31 (1.13 to 1.53)

1.32 (1.13 to 1.53)

 

P-value

1.61E-05

7.08E-06

0.13

5.14E-04

3.32E-04

  1. aCI, Confidence interval; OR, Odds ratio; SNP, Single-nucleotide polymorphism. Independence tests were performed using the two genome-wide association datasets. Conditional P-values <0.05 are shown in bold.