| | |
SNP whose effect is adjusted for
|
|---|
| | |
rs463426
|
rs131654
|
rs2266959
|
rs181359
|
rs5754217
|
rs2298428
|
|---|
|
rs463426
|
OR (95% CI)
| |
1.14 (1.01 to 1.27)
|
1.02 (0.91 to 1.14)
|
1.1 (0.98 to 1.23)
|
1.09 (0.98 to 1.23)
|
1.05 (0.94 to 1.17)
|
|
P-value
|
0.03
|
0.74
|
0.12
|
0.12
|
0.39
|
|
rs131654
|
OR (95% CI)
|
1.10 (0.98 to 1.24)
| |
0.95 (0.82 to 1.10)
|
0.99 (0.81 to 1.21)
|
0.94 (0.77 to 1.15)
|
0.96 (0.85 to 1.10)
|
|
P-value
|
0.09
|
0.51
|
0.92
|
0.57
|
0.59
|
|
rs2266959
|
OR (95% CI)
|
1.27 (1.14 to 1.43)
|
1.33 (1.16 to 1.53)
| |
1.37 (1.15 to 1.63)
|
1.36 (1.14 to 1.62)
|
0.79 (0.43 to 1.45)
|
|
P-value
|
3.02E-05
|
4.36E-05
|
4.69E-04
|
5.21E-04
|
0.44
|
|
rs181359
|
OR (95% CI)
|
1.16 (1.04 to 1.30)
|
1.25 (1.03 to 1.52)
|
0.92 (0.77 to 1.11)
| |
0.17 (0.01 to 3.89)
|
0.98 (0.83 to 1.14)
|
|
P-value
|
8.88E-03
|
0.02
|
0.39
|
0.27
|
0.76
|
|
rs5754217
|
OR (95% CI)
|
1.17 (1.04 to 1.31)
|
1.3 (1.08 to 1.57)
|
0.93 (0.77 to 1.11)
|
0.94 (0.77 to 1.11)
| |
0.98 (0.84 to 1.14)
|
|
P-value
|
7.21E-03
|
6.75E-03
|
0.41
|
0.20
|
0.79
|
|
rs2298428
|
OR (95% CI)
|
1.27 (1.14 to 1.41)
|
1.33 (1.18 to 1.51)
|
1.61 (0.87 to 2.95)
|
1.31 (1.13 to 1.53)
|
1.32 (1.13 to 1.53)
| |
|
P-value
|
1.61E-05
|
7.08E-06
|
0.13
|
5.14E-04
|
3.32E-04
|
-
aCI, Confidence interval; OR, Odds ratio; SNP, Single-nucleotide polymorphism. Independence tests were performed using the two genome-wide association datasets. Conditional P-values <0.05 are shown in bold.
