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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren’s syndrome

Figure 3

Comparison of inflammatory markers and T cell-related cytokines in LG of knockouts. Relative fold of expression of IL-1β, TNF-α, MHC II, IFN-γ, IL-13 and IFN-γ receptor. Data are presented as mean ± SEM of eight individual samples/strain/age. * P <0.05; ** P <0.01, *** P <0.001; **** P <0.0001 within strain comparison vs. 4 weeks. ^ P <0.05; ^^ P <0.01, ^^^ P <0.001; ^^^^ P <0.0001 interstrain comparison. IFN-γ, interferon-gamma; IL, interleukin; LG, lacrimal gland; MHC-II, major histocompatibility complex class II; SEM, standard error of the mean TNF-α, tumor necrosis factor alpha. R = receptor.

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