Characteristic | Total dataset | HLA-B allelotyped subset | ||
---|---|---|---|---|
Cases | Controls | Cases | Controls | |
Number | 973 | 825 | 681 | 414 |
Male gender, n/total n (%) | 511/973 (52.5) | 348/825 (42.2) | 480/681 (70.5) | 281/414 (67.9) |
Age at examination, years, mean ± SD | 39.1 ± 10.9 | 40.5 ± 11.9 | 39.2 ± 10.6 | 42.7 ± 11.5 |
Age at onset, years, mean ± SD | 26.0 ± 9.6 | 26.0 ± 9.5 | ||
Oral aphthosis, n/total n (%) | 962/973 (98.9) | 0/825 (0.0) | 672/681 (98.7) | 0/414 (0.0) |
Genital aphthosis, n/total n (%) | 609/973 (62.6) | 0/825 (0.0) | 424/681 (62.3) | 0/414 (0.0) |
Skin lesions, n/total n (%) | 539/973 (55.4) | 393/681 (57.7) | ||
Ophthalmologic manifestations, n/total n (%) | 583/973 (59.9) | 427/681 (62.7) | ||
Joint manifestations, n/total n (%) | 300/973 (30.8) | 218/681 (32.0) | ||
Neurological manifestations, n/total n (%) | 61/973 (6.3) | 42/681 (6.2) | ||
Vascular involvement, n/total n (%)) | 51/973 (5.2) | 43/681 (6.3) | ||
Gastrointestinal manifestations, n/total n (%) | 38/973 (3.9) | 22/681 (3.2) | ||
Pathergy phenomenon, n/total n (%) | 441/959 (46.0) | 323/669 (48.3) | ||
Family history of BD, n/total n (%) | 85/935 (9.1) | 57/651 (8.8) |