Table 2 HLA-B allele frequencies and their association with Behçet’s disease (BD)
HLA-B allelotyped dataset | HLA-B*51 negative individuals | |||||||
|---|---|---|---|---|---|---|---|---|
HLA-B allele | Cases | Controls | P -values | Odds ratio | Cases | Controls | P -values | Odds ratio |
(95% CI) | (95% CI) | |||||||
B*35 | 13.2% | 22.0% | 1.19 × 10 −7 | 0.54 (0.43, 0.68) | 22.2% | 25.3% | 2.72 × 10−1 | |
B*51 | 39.1% | 12.1% | 4.11 × 10 −41 | 4.63 (3.66, 5.85) | - | - | - | |
B*52 | 3.0% | 5.8% | 1.99 × 10 −3 | 0.50 (0.33, 0.77) | 5.3% | 6.5% | 4.72 × 10−1 | |
B*18 | 4.2% | 5.7% | 1.37 × 10−1 | 7.5% | 6.7% | 6.90 × 10−1 | ||
B*07 | 2.8% | 5.0% | 1.20 × 10 −2 | 0.55 (0.35, 0.86) | 4.2% | 5.6% | 3.62 × 10−1 | |
B*13 | 2.2% | 4.1% | 1.49 × 10 −2 | 0.53 (0.32, 0.87) | 3.7% | 4.7% | 5.58 × 10−1 | |
B*08 | 2.5% | 4.0% | 6.66 × 10−2 | 3.3% | 4.2% | 5.51 × 10−1 | ||
B*38 | 3.3% | 3.9% | 5.68 × 10−1 | 7.0% | 4.8% | 1.51 × 10−1 | ||
B*55 | 3.7% | 3.9% | 9.08 × 10−1 | 5.3% | 4.3% | 5.64 × 10−1 | ||
B*40 | 1.6% | 3.7% | 2.70 × 10 −3 | 0.42 (0.24, 0.73) | 2.2% | 4.0% | 1.31 × 10−1 | |
B*44 | 3.4% | 3.7% | 8.10 × 10−1 | 5.9% | 4.2% | 2.37 × 10−1 | ||
B*41 | 2.3% | 3.5% | 1.16 × 10−1 | 2.9% | 4.2% | 3.20 × 10−1 | ||
B*50 | 2.6% | 3.5% | 2.60 × 10−1 | 5.1% | 3.7% | 3.53 × 10−1 | ||
B*14 | 2.0% | 3.1% | 1.17 × 10−1 | 2.9% | 3.6% | 6.34 × 10−1 | ||
B*49 | 1.5% | 3.0% | 2.89 × 10 −2 | 0.50 (0.28, 0.90) | 1.8% | 3.4% | 1.42 × 10−1 | |
B*15 | 4.8% | 2.8% | 2.83 × 10 −2 | 1.75 (1.08, 2.84) | 7.5% | 3.3% | 2.51 × 10 −3 | 2.40 (1.37, 4.20) |
B*27 | 2.6% | 2.5% | 9.27 × 10−1 | 4.8% | 2.8% | 1.05 × 10−1 | ||
Other | 5.2% | 7.6% | 8.4% | 8.7% | ||||