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Figure 1 | Arthritis Research & Therapy

Figure 1

From: High mobility group box 1 contributes to anti-neutrophil cytoplasmic antibody-induced neutrophils activation through receptor for advanced glycation end products (RAGE) and Toll-like receptor 4

Figure 1

Dose–response curve for HMGB1 in priming neutrophils and a representative histogram of effects of HMGB1 on translocation of PR3 over time. (A) was a representative histogram of effects of HMGB1 on translocation of PR3 over time. The levels of mPR3 expression on neutrophils (B) and MPO in the supernatant of neutrophils (C) was roughly dose-dependent. Bars represent mean ± standard deviation (SD) of repeated measurements of three independent experiments. HMGB1, high mobility group box-1; MPO, myeloperoxidase; PR3, proteinase 3.

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Arthritis Research & Therapy

ISSN: 1478-6362

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