Table 2 Identification of signaling pathways based on Kyoto Encyclopedia of Genes and Genomes in differentially expressed genes
Path_Id | Path_name | Path_diffgenes | Path_genes | Enrichment | Q value |
|---|---|---|---|---|---|
4012 | ErbB signaling pathway | 12 | 87 | 28.122 | 4.88 × 10−14 |
4660 | T-cell receptor signaling pathway | 13 | 108 | 24.542 | 2.69 × 10−14 |
4150 | mTOR signaling pathway | 6 | 52 | 23.525 | 1.71 × 10−7 |
4350 | TGF-β signaling pathway | 10 | 87 | 23.435 | 2.63 × 10−11 |
4210 | Apoptosis | 10 | 89 | 22.909 | 3.01 × 10−11 |
4062 | Chemokine signaling pathway | 18 | 192 | 19.114 | 1.52 × 10−17 |
4010 | MAPK signaling pathway | 23 | 271 | 17.304 | 2.14 × 10−21 |
4630 | Jak-STAT signaling pathway | 12 | 155 | 15.785 | 2.44 × 10−11 |
4310 | Wnt signaling pathway | 11 | 152 | 14.755 | 2.78 × 10−10 |
4620 | Toll-like receptor signaling pathway | 5 | 101 | 10.093 | 9.23 × 10−5 |
4060 | Cytokine-cytokine receptor interaction | 12 | 263 | 9.303 | 6.59 × 10−9 |
5322 | Systemic lupus erythematosus | 5 | 140 | 7.282 | 3.47 × 10−4 |