Table 2 Comparison of variables between patients who were or were not reclassified as systemic sclerosis according to the 2013 ACR/EULAR classification criteria for systemic sclerosis
Variables | Patients reclassified as systemic sclerosis (N = 17) | Patients not reclassified as systemic sclerosis (N = 47) | P value | P value * |
|---|---|---|---|---|
Characteristics | ||||
Age (years old) | 48.9 ± 12.4 | 51.7 ± 15.1 | NS | |
Sex, female (N (%)) | 17 (100) | 41 (87.2) | NS | |
Raynaud’s phenomenon duration (years) | 3.4 ± 2.4 | 6.1 ± 9.0 | NS | |
The 2013 ACR/EULAR classification criteria score | 10.5 ± 1.8 | 6.1 ± 1.7 | <0.001 | <0.001 |
Autoimmune disease accompanied (N (%)) | 10 (58.8) | 23 (48.9) | NS | |
Sjögren syndrome | 4 (23.5) | 11 (223.4) | NS | |
Systemic lupus erythematosus | 4 (23.5) | 4 (8.5) | NS | |
Mixed connective tissue disease | 2 (11.8) | 3 (6.4) | NS | |
Rheumatoid arthritis | 2 (11.8) | 1 (2.1) | NS | |
Inflammatory myopathy | 1 (5.9) | 1 (2.1) | NS | |
Clinical manifestations (N (%)) | ||||
Scleroderma (proximal) | 0 (0) | 0 (0) | NS | |
Puffy finger | 12 (70.6) | 22 (46.8) | NS | |
Sclerodactyly | 6 (35.2) | 1 (2.1) | <0.001 | <0.001 |
Digital tip ulcer | 2 (11.8) | 0 (0) | 0.017 | 0.034 |
Fingertip pitting scar | 0 (0) | 0 (0) | NS | |
Telangiectasia | 5 (29.4) | 2 (4.3) | 0.004 | 0.008 |
Abnormal nailfold capillaries | 17 (100) | 29 (61.7) | 0.003 | 0.006 |
Pulmonary arterial hypertension | 0 (0) | 1 (2.1) | NS | |
Interstitial lung disease* | 2 (11.8) | 3 (6.4) | NS | |
Autoantibodies (N (%)) | ||||
Antinuclear antibody (centromere) | 9 (52.9) | 16 (34.0) | NS | |
Anti-centromere antibody | 11 (64.7) | 11 (23.4) | 0.002 | 0.004 |
Anti-Scl-70 antibody | 0 (0) | 2 (4.3) | NS |