Table 3 Comparison of variables between patients who were newly classified as systemic sclerosis according to the 2013 ACR/EULAR classification criteria for systemic sclerosis and those who had been previously classified
Variables | Patients newly classified as systemic sclerosis (N = 17) | Patients previously classified as systemic sclerosis (N = 60) | P value | P value * |
|---|---|---|---|---|
Characteristics | ||||
Age (years old) | 48.9 ± 12.4 | 51.1 ± 13.1 | NS | |
Sex, female (N (%)) | 17 (100) | 52 (86.7) | NS | |
The 2013 ACR/EULAR classification criteria score | 10.5 ± 1.8 | 19.1 ± 5.1 | <0.001 | <0.001 |
Clinical manifestations (N (%)) | ||||
Scleroderma (proximal) | 0 (0) | 40 (66.7) | <0.001 | <0.001 |
Puffy finger | 12 (70.6) | 27 (45.0) | NS | |
Sclerodactyly | 6 (35.2) | 55 (91.7) | <0.001 | <0.001 |
Digital tip ulcer | 2 (11.8) | 20 (33.3) | NS | |
Fingertip pitting scar | 0 (0) | 19 (31.7) | 0.008 | 0.016 |
Telangiectasia | 5 (29.4) | 5 (8.3) | 0.022 | 0.044 |
Abnormal nailfold capillaries | 17 (100) | 56 (93.3) | NS | |
Pulmonary arterial hypertension | 0 (0) | 3 (5.0) | NS | |
Interstitial lung disease* | 2 (11.8) | 29 (48.3) | 0.007 | 0.014 |
Autoantibodies (N (%)) | ||||
Antinuclear antibody (centromere) | 9 (52.9) | 12 (20.0) | 0.007 | 0.014 |
Anti-centromere antibody | 11 (64.7) | 13 (21.6) | 0.001 | 0.002 |
Anti-Scl-70 antibody | 0 (0) | 29 (48.3) | <0.001 | <0.001 |