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Table 3 Comparison of variables between patients who were newly classified as systemic sclerosis according to the 2013 ACR/EULAR classification criteria for systemic sclerosis and those who had been previously classified

From: Application of the 2013 ACR/EULAR classification criteria for systemic sclerosis to patients with Raynaud’s phenomenon

Variables Patients newly classified as systemic sclerosis (N = 17) Patients previously classified as systemic sclerosis (N = 60) P value P value *
Characteristics     
  Age (years old) 48.9 ± 12.4 51.1 ± 13.1 NS  
  Sex, female (N (%)) 17 (100) 52 (86.7) NS  
The 2013 ACR/EULAR classification criteria score 10.5 ± 1.8 19.1 ± 5.1 <0.001 <0.001
Clinical manifestations (N (%))     
  Scleroderma (proximal) 0 (0) 40 (66.7) <0.001 <0.001
  Puffy finger 12 (70.6) 27 (45.0) NS  
  Sclerodactyly 6 (35.2) 55 (91.7) <0.001 <0.001
  Digital tip ulcer 2 (11.8) 20 (33.3) NS  
  Fingertip pitting scar 0 (0) 19 (31.7) 0.008 0.016
  Telangiectasia 5 (29.4) 5 (8.3) 0.022 0.044
  Abnormal nailfold capillaries 17 (100) 56 (93.3) NS  
  Pulmonary arterial hypertension 0 (0) 3 (5.0) NS  
  Interstitial lung disease* 2 (11.8) 29 (48.3) 0.007 0.014
Autoantibodies (N (%))     
  Antinuclear antibody (centromere) 9 (52.9) 12 (20.0) 0.007 0.014
  Anti-centromere antibody 11 (64.7) 13 (21.6) 0.001 0.002
  Anti-Scl-70 antibody 0 (0) 29 (48.3) <0.001 <0.001
  1. Values are expressed as N (%) or mean ± standard deviation. P value* = Bonferroni-adjusted P value among variables with statistical significance. ACR, American College of Rheumatology; EULAR, The European League Against Rheumatism; NS, not significant.