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Table 3 Bone mineral density (BMD) in all patients with systemic lupus erythematosus (SLE) and sex- and age-matched controls (*subanalysis of postmenopausal women only)

From: Bone mineral density and carotid atherosclerosis in systemic lupus erythematosus: a controlled cross-sectional study

  SLE, n = 111 Controls, n = 111 P -value
BMD, mg/cm 2    
Total body 1.119 (0.127) 1.130 (0.137) 0.563
 Postmenopausal women* 1.056 (0.106) 1.064 (0.017) 0.724
Lumbar spine, vertebrae L1 to L4 1.134 (0.120) 1.153 (0.177) 0.456
 Postmenopausal women* 1.058 (0.221) 1.075 (0.180) 0.668
Total hip 0.959 (0.151) 0.998 (0.139) 0.046
 Postmenopausal women* 0.903 (0.126) 0.949 (0.138) 0.087
Femoral neck 0.909 (0.142) 0.958 (0.162) 0.017
 Postmenopausal women* 0.846 (0.110) 0.893 (0.128) 0.048
T-score:    
Total body 0.27 (1.20) 0.35 (1.23) 0.620
 Postmenopausal women* −0.23 (1.04) −0.16 (1.22) 0.754
Lumbar spine, vertebrae L1 to L4 −0.45 (1.38) −0.38 (1.41) 0.683
 Postmenopausal women* −0.96 (1.46) −0.97 (1.46) 0.974
Total hip −0.42 (1.24) −0.10 (1.09) 0.045
 Postmenopausal women* −0.82 (1.07) −0.43 (1.15) 0.084
Femoral neck −0.66 (1.18) −0.32 (1.07) 0.026
 Post-menopausal women* −1.12 (0.92) −0.73 (1.06) 0.054
BMD groups    
Normal total body BMD 32 (28.8%) 45 (40.5%) 0.067
 Postmenopausal women* 6 (12.5%) 11 (21.2%) 0.250
Low BMD, lumbar spine 60 (54.1%) 52 (46.8%) 0.283
 Postmenopausal women* 33 (68.8%) 36 (69.2%) 0.959
Low BMD, total hip 64 (57.7%) 50 (45%) 0.060
 Postmenopausal women* 35 (72.9%) 33 (63.5%) 0.311
Low BMD, femoral neck 69 (62.2%) 58 (52.3%) 0.136
 Postmenopausal women* 38 (79.2%) 37 (73.1%) 0.476
Low BMD, at least one region 79 (71.2%) 66 (59.5%) 0.067
 Postmenopausal women* 42 (87.5%) 41 (78.8%) 0.250
Treatments for osteoporosis, n (%):    
Calcium supplement and/or vitamin D 71 (64.0%) 7 (6.3%) <0.001
 Postmenopausal women* 34 (70.8%) 6 (11.5%) <0.001
Bisphosphonates 14 (12.6%) 4 (3.6%) 0.014
 Postmenopausal women* 10 (20.8%) 4 (7.7%) 0.058
Hormone replacement therapy 2 (1.8%) 3 (2.7%) 1.0
 Postmenopausal women* 2 (4.2%) 3 (5.8%) 1.0
  1. Values are number (percentage and mean (SD)). P-values indicate between-group differences. Low BMD is defined as a T-score < −1.0 SD.