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Table 1 Patients’ characteristics at baseline per treatment group a

From: Patients lacking classical poor prognostic markers might also benefit from a step-down glucocorticoid bridging scheme in early rheumatoid arthritis: week 16 results from the randomized multicenter CareRA trial

 

MTX-TSU

COBRA Slim

n = 47

n = 43

Age (yr)

51.02 ± 14.00

51.42 ± 14.42

BMI (kg/m2)

26.98 ± 4.22

25.40 ± 4.27

Female sex

80.9%

76.7%

Smoking status (ever)

38.3%

48.2%

Alcohol intake (yes)

61.7%

55.8%

Symptom duration (wk)

33.11 ± 62.21

34.42 ± 68.16

Disease duration (wk)

3.17 ± 6.62

1.86 ± 2.70

Employed before onset (yes)

66.0%

55.8%

Currently employed (yes)

57.4%

51.2%

Comorbidities present (yes)

66.0%

60.5%

Nocturnal pain (yes)

72.3%

48.8%

Morning stiffness (yes)

68.1%

53.5%

RF (yes)

23.4%

25.6%

Anti-CCP (yes)

23.4%

27.9%

Erosions (yes)

0.0%

2.3%

Total TJC

14.06 ± 8.61

13.14 ± 10.70

Total SJC

10.00 ± 6.98

10.93 ± 7.55

TJC28

9.49 ± 7.46

8.51 ± 7.80

SJC28

6.89 ± 6.11

7.79 ± 6.03

PGA (range: 0 to 100)

49.89 ± 22.99

48.60 ± 30.68

Pain (range: 0 to 100)

52.09 ± 23.23

48.23 ± 31.19

Fatigue (range: 0 to 100)

45.91 ± 22.07

39.40 ± 27.66

PhGA (range: 0 to 100)

48.34 ± 23.37

48.63 ± 20.80

ESR (mm/hr)

23.04 ± 16.90

30.00 ± 29.40

CRP (mg/L)

13.53 ± 18.62

20.14 ± 39.25

DAS28(ESR)

4.83 ± 1.68

4.88 ± 1.64

DAS28(CRP)

4.55 ± 1.63

4.50 ± 1.63

HAQ (range: 0 to 3)

0.99 ± 0.67

0.92 ± 0.85

  1. aAlcohol intake, Consumption of any form of alcohol; Anti-CCP, Anti–citrullinated protein antibodies; BMI, Body mass index; COBRA Slim, COmbinatie therapie bij Reumatoïde Artritis; CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; Disease duration, Time elapsed between diagnosis of RA and start of treatment; ESR, Erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; Morning stiffness, Being stiff in the morning for at least 45 minutes; MTX-TSU, Methotrexate with tight step-up, 15 mg of MTX weekly, no oral steroids allowed; PGA, Patient global assessment; PhGA, Physician global assessment; RF, Rheumatoid factor; SJC, Swollen joint count; Symptom duration, Time elapsed between onset of symptoms and start of treatment; TJC, Tender joint count. Values reported are proportions or mean ± standard deviation.