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Table 4 HLA-DRB1 alleles and association with hAPLN

From: Histological antiphospholipid-associated nephropathy versus lupus nephritis in patients with systemic lupus erythematosus: an observational cross-sectional study with longitudinal follow-up

HLA-DRB1 All patients LN hAPLN P value (after Bonferroni adjustment) P value
(n = 110*) (n = 94) (n = 16)
*01 16 (15) 16 (17) 0 (0) NS 0.1
*03 43 (39) 36 (38) 7 (44) NS 0.7
*04 23 (21) 20 (21) 3 (19) NS NS
*07 12 (11) 11 (12) 1 (6) NS NS
*08 7 (6) 6 (6) 1 (6) NS NS
*09 4 (4) 4 (4) 0 (0) NS NS
*10 3 (3) 2 (2) 1 (6) NS 0.4
*11 11 (10) 11 (12) 0 (0) NS 0.4
*12 4 (4) 4 (4) 0 (0) NS NS
*13 28 (26) 19 (20) 9 (56) 0.03 0.002
*14 4 (4) 3 (3) 1 (6) NS 0.5
*15 49 (45) 44 (47) 5 (31) NS 0.3
*16 3 (3) 2 (2) 1 (6) NS 0.4
  1. Values are shown as n (%). P values are comparisons between the two diagnostic groups: lupus nephritis (LN) and histopathological antiphospholipid-associated nephropathy (hAPLN). NS, not significant. *Genetic analysis had not been performed on two of the patients.