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Table 4 HLA-DRB1 alleles and association with hAPLN

From: Histological antiphospholipid-associated nephropathy versus lupus nephritis in patients with systemic lupus erythematosus: an observational cross-sectional study with longitudinal follow-up

HLA-DRB1

All patients

LN

hAPLN

P value (after Bonferroni adjustment)

P value

(n = 110*)

(n = 94)

(n = 16)

*01

16 (15)

16 (17)

0 (0)

NS

0.1

*03

43 (39)

36 (38)

7 (44)

NS

0.7

*04

23 (21)

20 (21)

3 (19)

NS

NS

*07

12 (11)

11 (12)

1 (6)

NS

NS

*08

7 (6)

6 (6)

1 (6)

NS

NS

*09

4 (4)

4 (4)

0 (0)

NS

NS

*10

3 (3)

2 (2)

1 (6)

NS

0.4

*11

11 (10)

11 (12)

0 (0)

NS

0.4

*12

4 (4)

4 (4)

0 (0)

NS

NS

*13

28 (26)

19 (20)

9 (56)

0.03

0.002

*14

4 (4)

3 (3)

1 (6)

NS

0.5

*15

49 (45)

44 (47)

5 (31)

NS

0.3

*16

3 (3)

2 (2)

1 (6)

NS

0.4

  1. Values are shown as n (%). P values are comparisons between the two diagnostic groups: lupus nephritis (LN) and histopathological antiphospholipid-associated nephropathy (hAPLN). NS, not significant. *Genetic analysis had not been performed on two of the patients.