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Table 1 Baseline characteristics of the arthralgia patients

From: Reappraisal of the diagnostic and prognostic value of morning stiffness in arthralgia and early arthritis: results from the Groningen EARC, Leiden EARC, ESPOIR, Leiden EAC and REACH

 

Leiden EA R C

Groningen EA R C

REACH

All n = 807

No arthritis n = 435

Arthritis n = 372

All n = 481

No arthritis n = 214

Arthritis n = 267

All n = 353

No arthritis n = 172

Arthritis n = 181

Age, mean ± SD, years

51.4 ± 16.3

49.6 ± 15.5

53.5 ± 17.0

51.6 ± 16.4

49.0 ± 15.3

53.7 ± 16.9

48.6 ± 14.1

46.7 ± 11.7

50.3 ± 15.9

Female, n (%)

574 (71)

345 (79)

229 (62)

311 (65)

145 (68)

166 (62)

277 (79)

149 (87)

128 (71)

Gradual onset symptoms, n (%)

499 (62)

285 (67)

214 (59)

299 (63)

140 (66)

159 (61)

183 (58)

115 (71)

68 (44)

Morning stiffness, minutes

10 (0–30)

10 (0–30)

10 (0–30)

10 (0–30)

10 (0–30)

15 (0–60)

30 (0–60)

30 (0–60)

30 (0–97)

≥30 minutes, n (%)

210 (30)

106 (28)

104 (32)

146 (36)

55 (30)

91 (40)

185 (53)

87 (52)

98 (54)

≥60 minutes, n (%)

129 (18)

60 (16)

69 (21)

88 (22)

27 (15)

61 (27)

114 (32)

45 (27)

68 (38)

≥90 minutes, n (%)

71 (10)

27 (7)

44 (14)

53 (13)

15 (8)

38 (17)

73 (21)

25 (15)

48 (27)

Tender joint count

7 (2–14)

8 (3–17)

5 (2–13)

9 (4–18)

9 (4–18)

8 (3–18)

7 (3–12)

7 (2–12)

7 (3–11)

Symptom duration, weeks

11.5 (4.0-61.0)

19.3 (6.1-122)

6.9 (2.7-21.6)

18.0 (5.6-64.3)

22.9 (6.9-74.9)

16.6 (4.6-54.9)

1.7 (0.8-3.2)

2.4 (1.2-3.6)

1.3 (0.7-2.3)

<12 weeks symptom duration, n (%)

380 (51)

162 (41)

218 (62)

165 (39)

70 (38)

95 (39)

352 (100)

171 (100)

181 (100)

  1. Values are median (interquartile range) unless indicated otherwise. Missingness per variable as follows: gradual onset symptoms (defined as start of onset >1 week) Leiden EARC n = 17, Groningen EARC n = 8, REACH n = 36); morning stiffness Leiden EARC n = 101, Groningen EARC n = 72, REACH n = 5; tender joint count Groningen EARC n = 1; symptom duration/ <12 weeks symptom duration Leiden EARC n = 61, Groningen EARC n = 54, REACH n = 1. Patients with missing data on morning stiffness duration did not differ significantly from patients with data on morning stiffness (data not shown). EARC, Early Arthritis Recognition Clinic; REACH, Rotterdam Early Arthritis Cohort; SD, standard deviation.