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Table 2 HLA-B phenotype frequencies in patients with HSP and controls

From: Association of HLA-B*41:02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status

HLA-B

Patients with HSP (number = 349)

Controls (number = 335)

P

OR (95% CI)

B*07

B*07:02

52 (14.9)

49 (14.6)

0.92

1.02 (0.65 to 1.60)

B*08

B*08:01

29 (8.3)

31 (9.2)

0.66

0.88 (0.50 to 1.56)

B*13

B*13:02

7 (2.0)

8 (2.4)

0.73

0.84 (0.25 to 2.67)

B*14

B*14:01

8 (2.3)

5 (1.5)

0.44

1.54 (0.44 to 6.07)

 

B*14:02

29 (8.3)

47 (14.0)

0.017

0.55 (0.33 to 0.93)

B*15

B*15:01

25 (7.2)

22 (6.6)

0.76

1.10 (0.58 to 2.10)

 

B*15:17

4 (1.2)

5 (1.5)

0.69

0.76 (0.15 to 3.60)

B*18

B*18:01

36 (10.3)

41 (12.2)

0.42

0.82 (0.49 to 1.36)

B*27

B*27:05

20 (5.9)

20 (6.0)

0.89

0.96 (0.48 to 1.91)

B*35

B*35:01

50 (14.3)

51 (15.2)

0.74

0.93 (0.59 to 1.45)

 

B*35:03

20 (5.7)

8 (2.4)

0.027

2.48 (1.02 to 6.61)

B*38

B*38:01

10 (3.0)

27 (8.1)

0.0027

0.34 (0.14 to 0.73)

B*39

B*39:01

8 (2.4)

7 (2.1)

0.85

1.10 (0.34 to 3.61)

B*40

B*40:01

16 (4.6)

17 (5.1)

0.76

0.89 (0.42 to 1.93)

 

B*40:02

10 (3.0)

5 (1.5)

0.22

1.94 (0.59 to 7.33)

B*41 a

B*41:01

6 (1.8)

6 (1.8)

0.94

0.95 (0.25 to 3.62)

 

B*41:02

28 (8.3)

5 (1.5)

0.0001

5.76 (2.15 to 19.3)

B*44

B*44:02

35 (10.0)

16 (4.8)

0.009

2.22 (1.17 to 4.39)

 

B*44:03

61 (17.5)

71 (21.2)

0.22

0.79 (0.53 to 1.17)

B*45

B*45:01

7 (2.0)

11 (3.3)

0.29

0.60 (0.19 to 1.73)

B*49

B*49:01

24 (7.2)

34 (10.1)

0.12

0.65 (0.36 to 1.16)

B*50

B*50:01

26 (7.7)

16 (4.8)

0.14

1.60 (0.81 to 3.26)

B*51

B*51:01

53 (15.2)

56 (16.7)

0.59

0.89 (0.58 to 1.37)

B*52

B*52:01

5 (1.5)

11 (3.3)

0.11

0.43 (0.11 to 1.35)

B*53

B*53:01

12 (3.6)

13 (3.9)

0.76

0.88 (0.36 to 2.13)

B*55

B*55:01

4 (1.2)

12 (3.6)

0.035

0.31 (0.07 to 1.04)

B*57

B*57:01

22 (6.3)

12 (3.6)

0.10

1.81 (0.84 to 4.10)

B*58

B*58:01

13 (3.7)

11 (3.3)

0.75

1.14 (0.46 to 2.85)

  1. a10.1% in HSP patients versus 3.3% in controls; P = 0.0007; OR = 3.18 (1.53 to 7.07); values are expressed as number (n) and percentages (%); the result that remained statistically significant after adjusting for Bonferroni correction (pBNF = 0.0028) is highlighted in bold. HLA: human leukocyte antigen; HSP: Henoch- Schönlein purpura; OR: odds ratio; CI: confidence interval.
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Arthritis Research & Therapy

ISSN: 1478-6362

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