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Table 3 HLA-B*41:02 and HLA-DRB1*01:03 are independently associated with increased susceptibility to HSP

From: Association of HLA-B*41:02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status

HLA-DRB1*01:03

HLA-B*41:02

Patients with HSP

Controls

P

OR (95% CI)

-

-

270

292

-

Ref.

-

+

23

5

0.0004

4.97 (1.8 to 16.9)

+

-

48

6

<0.001

8.65 (3.6 to 25.1)

+

+

1

0

0.2988

-

  1. HLA: human leukocyte antigen; HSP: Henoch- Schönlein purpura; OR: odds ratio; CI: confidence interval.