Table 3 Post-index clinical characteristics in the treatment-naïve propensity score-matched cohorts - (rates per 1,000 patient-years)
| Â | Total | Febuxostat | Allopurinol | Allopurinol vs. febuxostat |
|---|---|---|---|---|
(N = 1,746) | (N = 873) | (N = 873) | Incidence rate ratio | |
(95% confidence interval) | ||||
Kidney failure | 14.8 | 24.2 | 5.3 | 0.22 (0.08, 0.51) |
Kidney stones | 4.0 | 3.6 | 4.5 | 1.26 (0.32, 5.21) |
Dialysis | 7.4 | 7.9 | 6.8 | 0.85 (0.31, 2.27) |
Angina | 21.4 | 19.8 | 23.0 | 1.16 (0.67, 2.03) |
Diabetes | 76.0 | 85.6 | 66.4 | 0.78 (0.56, 1.08) |
Coronary artery disease | 80.1 | 75.1 | 85.3 | 1.13 (0.84, 1.53) |
Heart failure | 25.2 | 31.3 | 18.8 | 0.60 (0.35, 1.02) |
Myocardial infarction | 17.9 | 18.3 | 17.5 | 0.95 (0.52, 1.75) |
Stroke | 32.5 | 35.9 | 28.9 | 0.81 (0.51, 1.26) |
Peripheral arterial disease | 18.8 | 21.4 | 16.0 | 0.75 (0.40, 1.36) |
Osteoarthritis | 170.6 | 182.5 | 158.6 | 0.87 (0.70, 1.08) |
Hypertension | 231.0 | 234.4 | 227.5 | 0.97 (0.74, 1.27) |
Hyperlipidemia | 355.6 | 358.5 | 352.8 | 0.98 (0.80, 1.20) |
Alcohol abuse | 8.1 | 7.2 | 9.1 | 1.25 (0.50, 3.24) |