Table 4 Serum urate (sUA) and serum creatinine (SCr) results - febuxostat vs. allopurinol- overall propensity-matched population (n = 3,864)

Pre-index sUA result

2,137 (55.3)

1,082 (56.0)

1,055 (54.6)

0.38

  Number of sUA results

1.3 (0.7)

1.4 (0.8)

1.2 (0.5)

<0.001

  Final sUA result

8.3 (2.1)

8.4 (2.2)

8.3 (2.0)

0.70

  Average sUA result

8.4 (1.9)

8.5 (1.9)

8.4 (1.9)

0.06

Pre-index SCr result

2,298 (59.5)

1,151 (59.6)

1,147 (59.4)

0.90

  Number of SCr results

1.7 (1.3)

1.7 (1.2)

1.6 (1.4)

0.02

  Final SCr result

1.3 (0.6)

1.4 (0.6)

1.3 (0.6)

0.003

  Average SCr result

1.3 (0.6)

1.4 (0.6)

1.3 (0.6)

0.001

Post-index sUA result

3,864 (100)

1,932 (100)

1,932 (100)

–

  Number of sUA results

2.0 (1.6)

2.1 (1.7)

1.8 (1.5)

<0.001

  Average sUA result

6.5 (1.8)

6.4 (2.0)

6.6 (1.7)

<0.001

Post-index SCr result

3,492 (90.4)

1,747 (90.4)

1,745 (90.3)

0.91

  Number of SCr results

3.1 (3.3)

3.2 (3.1)

3.1 (3.4)

0.16

  Average SCr result

1.3 (0.6)

1.3 (0.6)

1.2 (0.6)

<0.001

Post-index sUA goal (<6.0 mg/dL)

2,039 (52.8)

1,130 (58.5)

909 (47.1)

<0.001

Time to sUA goal <6.0 mg/dL (days)

379 (339)

348 (319)

410 (355)

<0.001

Post-index sUA goal (<5.0 mg/dL)

1,120 (29.0)

699 (36.2)

421 (21.8)

<0.001

Time to sUA goal <5.0 mg/dL (days)

472 (354)

443 (332)

501 (372)

<0.001