Table 1 Demographics, pharmacological treatment, and ankylosing spondylitis (AS)-related clinical manifestations in patients with an ankylosing spondylitis diagnosis in the National Patient Register (1967 to 2009) according to the base case and strict case definitions
Base case definition | Strict case definition | ||||
|---|---|---|---|---|---|
Men | Women | Total | Total | ||
(N = 7,041) | (N = 3,989) | (N = 11,030) | (N = 8,538) | ||
Demographics | Mean (SD) | P -value | Mean (SD) | Mean (SD) | |
Age at diagnosis registration | 38.6 (11.4) | 38.6 (11.3) | 0.907 | 38.6 (11.4) | 39.1 (11.0) |
Age on 31 December 2009 | 48.6 (11.2) | 47.6 (11.5) | <0.001 | 48.3 (11.3) | 48.5 (10.9) |
Pharmacological treatment during 2009 † | N (% of total) | P -value ††† | N (% of total) | ||
NSAIDs | 3,724 (52.9) | 2,164 (54.2) | 0.169 | 5,888 (53.4) | 4,736 (55.5) |
Oral corticosteroids | 734 (10.4) | 557 (14.0) | <0.001 | 1,291 (11.7) | 1,078 (12.6) |
sDMARDs | 1,406 (20.0) | 841 (21.1) | 0.163 | 2,247 (20.4) | 1,937 (22.7) |
TNFi | 1,100 (15.6) | 471 (11.8) | <0.001 | 1,571 (14.2) | 1,442 (16.9) |
Any pharmacological treatment | 4,634 (65.8) | 2,653 (66.5) | 0.460 | 7,287 (66.1) | 5,974 (70.0) |
AS-related clinical manifestations (1967–2009) †† | N (% of total) | P -value | N (% of total) | ||
Anterior uveitis | 1,797 (25.5) | 797 (20.0) | <0.001 | 2,594 (23.5) | 2,109 (24.7) |
Psoriasis | 486 (6.9) | 320 (8.0) | 0.030 | 806 (7.3) | 669 (7.8) |
IBD | 571 (8.1) | 343 (8.6) | 0.371 | 914 (8.3) | 746 (8.7) |
Peripheral arthritis | 1,079 (15.3) | 864 (21.7) | <0.001 | 1,943 (17.6) | 1,568 (18.4) |
Hip arthroplasty | 527 (7.5) | 319 (8.0) | 0.331 | 846 (7.7) | 658 (7.7) |