Figure 1

Comparison of expression of four large intergenic noncoding RNAs (linc0949, linc0597, linc1992 and linc3995) between patients with SLE, patients with RA and healthy donors. Each symbol represents an individual patient; horizontal lines indicate median values. The expression levels of the four large intergenic noncoding RNAs (lincRNAs) in 102 patients with SLE, 54 patients with RA and 76 healthy donors were analyzed by real-time quantitative PCR and normalized by RPL13A level. (A) Decreased expression of linc0949 in patients with SLE versus patients with RA and healthy donors. (B) linc0597 expression was significantly reduced in patients with SLE versus patients with RA and healthy donors. No apparent difference was detected in the expression of linc1992 (C) and linc3995 (D) between patients with SLE, patients with RA and healthy donors. NS, Not significant. ***P < 0.001. HD, Healthy donors; RA, Rheumatoid arthritis; SLE, Systemic lupus erythematosus.