Correlation of ESR and CRP with global 11β-HSD1 activity in patients with early arthritis and established RA analysed individually. Correlation between (THF + 5αTHF)/THE ratios and: ESR in established RA patients (A), CRP in established RA patients (B), ESR in all patients with early persistent arthritis (C), CRP in all patients with early persistent arthritis (D), ESR in early persistent RA patients (E), CRP in early persistent RA patients (F), ESR in early resolving arthritis patients (G) and CRP in early resolving arthritis patients (H). Correlation coefficient (rho) and the significance of the correlation (P value) were calculated using Spearman’s correlation. ESR, erythrocyte sedimentation rate (mm/hour); CRP, C-reactive protein (mg/L). 11β-HSD, 11β-hydroxysteroid dehydrogenase type 1; CRP, C-reactive protein (mg/L); RA, rheumatoid arthritis.