Figure 2
From: Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys?
Possible effects of mesenchymal stem cells (MSCs) on regulatory T cell (Treg) and Th17 cell populations in rheumatoid arthritis (RA). CIA, collagen-induced arthritis; IFNγ, interferon-γ; IL-2, interleukin-2; MHC-I, class I major histocompatibility complex; RORγt, retinoic acid receptor-related orphan receptor γt; TGFβ, transforming growth factor β; TNFα, tumour necrosis factor α. Adapted from MacDonald et al., Arthritis Rheum 2011 [40].