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Table 1 Clinical characteristics of SSc patients included in the discovery and replication sets

From: A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis

  US cohort French cohort P -value
Patients genotyped, n* 152 1031  
Female 78 86 0.012
Diffuse cutaneous systemic sclerosis 35 31 0.578
Limited cutaneous systemic sclerosis 63 63 0.578
Anticentromere antibody-positive 22 41 <0.001
Anti-topoisomerase I antibody-positive 23 28 0.860
Interstitial lung disease 57 38 <0.001
Pulmonary hypertension 7 7 0.976
  1. *Unless otherwise indicated, values indicate percentages. Bold P-values are those that are statistically significant at P <0.05 (Student’s t-test).