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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Eicosapentaenoic acid and docosapentaenoic acid monoglycerides are more potent than docosahexaenoic acid monoglyceride to resolve inflammation in a rheumatoid arthritis model

Fig. 5

Effect of vitamin E treatment on eicosapentaenoic acid monoglyceride (MAG-EPA)-induced anti-inflammatory effects in complete Freund’s adjuvant (CFA) rats. a Hind paw thickness (mm) as a function of time (days) was measured in control, CFA, CFA + MAG-EPA-treated rats in the absence and presence of vitamin E (vit E). Results represent the mean ± standard error of the mean (n = 6 per group). b Typical western blots and subsequent quantitative analysis of paw homogenate fractions derived from control, CFA, CFA + MAG-EPA + vitamin E- and CFA+ MAG-EPA-treated rats using specific antibodies against cyclooxygenase (COX)-2 and β-actin. Staining densities in homogenates are expressed as a function of β-actin signals. (n = 6, *P <0.05). c Determination levels of IL-17A, IL-6, IL-1β and TNFα in plasma of control, CFA-treated, CFA + MAG-EPA-treated rats in the absence and presence of vitamin E, (n = 6, *P ≤0.05)

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Arthritis Research & Therapy

ISSN: 1478-6362

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