Fig. 2

Longitudinal analysis of T cell receptor (TCR) repertoire in systemic lupus erythematosus (SLE) patients. Clonotype frequency and relative ranks of the top 50 clones in SLE. The three time points in SLE patients represent quiescence (Q), pre-flare (PF) and flare (F). The elapsed time (months) from the first sample are indicated. Clones above the horizontal red line (>1Â %) denotes highly expanded clones (HEC)