Table 1 Systemic lupus erythematosus (SLE) subject characteristics
Subject/ethnicity | Disease stage/organ involved | Elapsed time (months) | PGA | SLEDAI | WBC (103/mm3) | C3 (mg/dl) | C4 (mg/dl) | Anti-dsDNA (U/ml) | Therapy |
|---|---|---|---|---|---|---|---|---|---|
SLE1/white | Quiescent | 0 | 0 | 2 | 3.93 | 146 | 22 | 40 | MMF/HCQ |
| Â | Pre-flare | 4 | 0 | 0 | 3.82 | 108 | 19 | 0 | MMF/HCQ |
| Â | Flare (skin) | 6 | 1.5 | 10 | 4.34 | 115 | 21 | 80 | MMF/HCQ |
SLE2/white | Quiescent | 0 | 0 | 2 | 5.6 | 85 | 2 | 0 | Pred/MMF |
| Â | Pre-flare | 3 | 0.5 | 2 | 5.5 | 88 | 3 | 0 | Pred/MMF |
| Â | Flare (skin) | 5 | 2 | 10 | 7.8 | 105 | 4 | 0 | Pred/MMF |
SLE3/white | Quiescent | 0 | 0.5 | 2 | 6.26 | 86 | 11 | 0 | Pred |
| Â | Pre-flare | 5 | 0.5 | 2 | 7.04 | 86 | 11 | 0 | Pred |
| Â | Flare (skin) | 7 | 2 | 10 | 4.53 | 85 | 11 | 0 | Pred |
SLE4/white | Quiescent | 0 | 0 | 0 | 6.44 | 96 | 21 | 0 | Pred/AZA |
| Â | Pre-flare | 3 | 0 | 0 | 8.13 | 106 | 22 | 0 | Pred/AZA |
| Â | Flare (joint) | 6 | 1.5 | 4 | 7.96 | 102 | 22 | 0 | Pred/AZA |
SLE5/white | Quiescent | 0 | 0 | 0 | 2.68 | 108 | 21 | 0 | MMF/HCQ |
| Â | Pre-flare | 3 | 0 | 0 | 1.78 | 98 | 17 | 0 | MMF/HCQ |
| Â | Flare (renal) | 7 | 1.5 | 10 | 1.85 | 81 | 13 | 40 | MMF/HCQ |
SLE6/black | Quiescent | 0 | 0 | 0 | 13.35 | 134 | 19 | 0 | Pred/HCQ |
| Â | Pre-flare | 3 | 0.5 | 0 | 9.16 | 135 | 26 | 0 | HCQ |
| Â | Flare (renal) | 6 | 1.5 | 4 | 10.35 | 121 | 21 | 0 | HCQ |
SLE7/black | Quiescent | 0 | 0 | 0 | 5.3 | 134 | 35 | 0 | AZA/HCQ |
| Â | Pre-flare | 3 | 0 | 0 | 6.3 | 139 | 38 | 0 | AZA/HCQ |
| Â | Flare (joint) | 14 | 1.5 | 0 | 4.4 | 145 | 40 | 0 | AZA/HCQ |
SLE8/white | Quiescent | 0 | 0 | 0 | 5.53 | 106 | 21 | 0 | HCQ |
| Â | Pre-flare | 4 | 0 | 0 | 5.83 | 97 | 17 | 0 | HCQ |
| Â | Flare (skin) | 7 | 1 | 18 | 4.72 | 94 | 18 | 0 | HCQ |
SLE9/black | Quiescent | 0 | 0 | 0 | 5.75 | 161 | 39 | 0 | Pred/MMF |
| Â | Pre-flare | 3 | 0 | 0 | 5.83 | 145 | 29 | 0 | Pred/MMF |
| Â | Flare (renal) | 9 | 1.6 | 6 | 7.08 | 186 | 29 | 0 | Pred/MMF |
SLE10/black | Quiescent | 0 | 0.5 | 2 | 7.3 | 144 | 60 | 0 | Pred/HCQ |
| Â | Pre-flare | 4 | 0.5 | 0 | 6.93 | 90 | 38 | 0 | Pred/HCQ |
| Â | Flare (renal) | 6 | 2.5 | 6 | 6.62 | 97 | 43 | 0 | Pred/HCQ |
SLE11/white | Quiescent | 0 | 0.5 | 0 | 7.26 | 146 | 27 | 0 | Pred/LFM |
| Â | Pre-flare | 3 | 0 | 0 | 7.14 | 132 | 33 | 0 | Pred/LFM |
| Â | Flare (joint) | 7 | 1.5 | 6 | 7.18 | 139 | 26 | 0 | Pred/LFM |