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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus

Fig. 2

a, b IL-21 induced STAT3 phosphorylation. PBMCs from systemic lupus erythematosus (SLE) patients (black line) and healthy controls (HC) (dotted line) were stimulated with IL-21, and levels of phosphorylated STAT3 (pSTAT3) at tyrosine 705 (Y705) (a) and serine 727 (S727) (b) was measured in CD4+ T cells, B cells, and natural killer (NK) cells from SLE patients and HC (both n = 8). Graph shows median fluorescence intensity (MFI) with interquartile range. *p < 0.05, ****p < 0.0001 (RM two-way ANOVA)

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Arthritis Research & Therapy

ISSN: 1478-6362

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