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Table 1 Clinical characteristics of systemic lupus erythematosus patients and age- and gender-matched healthy controls

From: Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus

Parameters

SLE patients

HCs

 

(n = 14)

(n = 12)

Age (years)

41.0 (26.0–52.0)

43.0 (30.0–51.0)

Gender (% female)

100

100

Disease duration (years)

4.6 (2.2–11.4)

-

SLEDAI

4.0 (2.5–6.0)

-

SLICC

0.0 (0.0–1.0)

-

dsDNA (% ever positive)

79.0

-

dsDNA (IU/mL)

31.5 (10.8–396.8)

-

Clinical features (no. of patients)

 Nephritis

0

-

 Arthritis

4

-

 Rash

7

-

 Serositis

2

-

 Leukopenia

6

-

 Oral ulcers

4

-

 Vasculitis

1

-

Treatment (no. of patients)

 None

2

-

 Hydroxychloroquine

6

-

 Azathioprine

4

-

 Cyclophosphamide

1

-

 Mycophenolate mofetil

3

-

 Prednisone

12

-

  1. Values are shown as median (interquartile range) or as number where indicated. dsDNA double-stranded DNA, HC healthy control, SLE systemic lupus erythematosus, SLEDAI SLE Disease Activity Index, SLICC Systemic Lupus International Collaborating Clinics