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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren’s contracture

Fig. 4

Laminins 411/421 and 511/521 localize in the small blood vessels in DC. The DC samples were stained with antibodies recognizing laminin subunits α4, α5, β1, β2 and γ1; vWF and SMA as indicated on the panels. SMA-labeled myofibroblast layer surrounds the vWF-positive endothelium in the blood vessels found in the DC tissue (a). Laminin subunits β1, β2, α4, α5 and γ1 (b, c, d, e and f) localize in the SMA- (b, c) or vWF-labeled (d, e, f) small blood vessels. Scale bars: 100 μm. DC Dupuytren’s contracture, SMA smooth muscle actin, vWF von Willebrand’s factor

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