Fig. 2
From: Pneumococcal polysaccharide vaccination in rheumatoid arthritis patients receiving tacrolimus
Comparison of post-vaccination parameters in patients receiving TAC monotreatment or TAC/MTX combination treatment. a Percentage of patients with an increase in 6B and 23F serotype-specific IgG concentration greater than twofold. *P = 0.005, **P = 0.028, ***P = 0.001, for TAC compared with TAC/MTX. b Percentage of patients with an increase in OI for serotypes 6B and 23F greater than 10-fold. *P < 0.0001 for TAC compared with TAC/MTX. Data were compared by using the chi-squared test or Fisher’s exact probability test. MTX methotrexate, OI opsonization index, TAC tacrolimus