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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study

Fig. 5

Neutrophil phagocytosis capacity. a Representative example of gating of neutrophils in the leukocyte population using forward side-scatter characteristics. b Representative example of gating of phRodo positive-neutrophils (phycoerythrin (PE) channel) within the neutrophil gate. c Phagocytic index calculated using the formula: pHrodo positive neutrophils × MFI of pHrodo-positive neutrophils. Data in panel c are expressed as mean and SEM of 10 subjects per group. Within-group changes over time were not significant (p = 0.38 and p = 0.14 for the sham and tVNS groups, respectively, calculated using repeated measures one-way ANOVA). p-values depicted indicate differences between groups over time calculated using repeated measures two-way ANOVA (interaction term). AU arbitrary units, FS forward scatter, LPS lipopolysaccharide, SS side scatter, tVNS transvenous vagus nerve stimulation

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