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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE)

Fig. 2

Cumulative probability plot for time to achieve first low disease activity (LDA)/remission or sustained LDA/remission. Cumulative probability plot to achieve (a) first Simplified Disease Activity Index (SDAI) LDA, (b) first sustained SDAI LDA, (c) first SDAI remission, and (d) first sustained SDAI remission over 12 months (Kaplan–Meier estimation), based on patients with data available at baseline, month 6 and month 12. Cumulative probability and corresponding 95 % CI were computed using Kaplan–Meier limit-product estimators. Patients who lost first LDA or remission status were censored at the time of remission loss. SDAI LDA = SDAI ≤11; SDAI remission = SDAI ≤3.3; sustained remission was defined as maintained first LDA or remission at all subsequent visits up to 12 months. Median time to achieve outcome corresponds to the time point when 50 % of patients achieved the outcome. Median time was therefore not calculated if <50 % of patients achieved the outcome over the 12-month period. Median times (95 % CI) to first SDAI LDA and first SDAI remission for the abatacept plus methotrexate (MTX) arm were 140.0 and 371.0 days, respectively. Median time (95 % CI) to first SDAI LDA for the MTX arm was 197 days. Median time to achieve first SDAI remission cannot be defined in the MTX arm

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