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Table 1 Demographic, disease features and therapy of patients with giant cell arteritis at disease onset and Takayasu arteritis

From: High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins

Variables

GCA

HC

p

Variables

TA

HC

p

(n = 18)

(n = 16)

(n = 29)

(n = 29)

Demographic features

Age, years

72.0 (63.7–75.0)

68.5 (63.0–72.0)

0.643

Age, years

38.0 (34.5–48.5)

38.0 (27.5–48.5)

0.392

Females, n (%)

14 (77.8)

11 (68.8)

0.551

Females, n (%)

28 (96.6)

27 (93.1)

0.553

Disease features and therapy

GCA

Results

TA

Results

Headache, n (%)

12 (66.7)

Disease duration, months

108 (60–186)

Constitutional symptoms, n (%)

8 (44.4)

Angiographic type V, n (%)

16 (55.2)

Cranial ischemic manifestations, n (%)

8 (44.4)

Previous ischemic events, n (%)

11 (37.9)

Jaw claudication, n (%)

6 (33.3)

Active disease, n (%)

11 (37.9)

Visual symptoms, n (%)

4 (22.2)

Remission, n (%)

18 (62.1)

Polymyalgia rheumatica, n (%)

4 (22.2)

Statins, n (%)

16 (55.2)

Headache, n (%)

12 (66.7)

Prednisone, n (%)

16 (55.2)

ESR, mm/1st hour

69.6 ± 28.7

Prednisone daily dose, mg

8.7 (5.0–28.7)

CRP, mg/l

40.0 (20.2–84.2)

Immunosuppressive agents, n (%)

19 (65.5)

Positive TAB, n/total

8/11

Biological agents, n (%)

9 (31.0)

Positive PET-CT scan, n/total

13/15

  
  1. Continuous variables are presented as mean ± standard deviation or as median and interquartile range
  2. CRP C-reactive protein, ESR erythrocyte sedimentation rate, GCA giant cell arteritis, HC healthy controls, n number of patients, PET-CT positron emission computed tomography, TA Takayasu arteritis, TAB temporal artery biopsy