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Table 2 Comparison between patients with Takayasu arteritis with active disease and in remission

From: High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins

Variables

Active disease (n = 11)

Remission (n = 18)

p

HMGB1, ng/ml

1.31 (0.63–2.16)

0.75 (0.39–2.05)

0.281

ESR, mm/1st hour

39.0 (25.0–68.0)

17.5 (8.0–25.5)

0.017

CRP, mg/l

6.0 (4.4–24.9)

2.0 (0.1–10.7)

0.053

ITAS2010

3.0 (2.2–5.2)

--

--

ITAS.A ESR

3.5 (2.0–6.2)

1.0 (1.0–1.7)

0.001

ITAS.A CRP

5.1 ± 2.5

2.1 ± 0.9

0.012

Statins, n (%)

7 (63.6)

9 (50.0)

0.702

Prednisone, n (%)

6 (54.5)

10 (55.6)

0.958

Prednisone daily dose, mg

20.0 (7.5–45.0)

5.0 (2.5–13.7)

0.055

Immunosuppressive agents, n (%)

7 (63.6)

12 (66.7)

0.868

Biological agents, n (%)

3 (27.3)

6 (33.3)

0.732

  1. Continuous variables are presented as median and interquartile range or as mean ± standard deviation
  2. CRP C-reactive protein, ESR erythrocyte sedimentation rate, ITAS Indian Takayasu activity score, ITAS.A Indian Takayasu activity score with acute phase response, HMGB1 high mobility group box 1, n number of patients