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Table 2 Comparison between patients with Takayasu arteritis with active disease and in remission

From: High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins

Variables Active disease (n = 11) Remission (n = 18) p
HMGB1, ng/ml 1.31 (0.63–2.16) 0.75 (0.39–2.05) 0.281
ESR, mm/1st hour 39.0 (25.0–68.0) 17.5 (8.0–25.5) 0.017
CRP, mg/l 6.0 (4.4–24.9) 2.0 (0.1–10.7) 0.053
ITAS2010 3.0 (2.2–5.2) -- --
ITAS.A ESR 3.5 (2.0–6.2) 1.0 (1.0–1.7) 0.001
ITAS.A CRP 5.1 ± 2.5 2.1 ± 0.9 0.012
Statins, n (%) 7 (63.6) 9 (50.0) 0.702
Prednisone, n (%) 6 (54.5) 10 (55.6) 0.958
Prednisone daily dose, mg 20.0 (7.5–45.0) 5.0 (2.5–13.7) 0.055
Immunosuppressive agents, n (%) 7 (63.6) 12 (66.7) 0.868
Biological agents, n (%) 3 (27.3) 6 (33.3) 0.732
  1. Continuous variables are presented as median and interquartile range or as mean ± standard deviation
  2. CRP C-reactive protein, ESR erythrocyte sedimentation rate, ITAS Indian Takayasu activity score, ITAS.A Indian Takayasu activity score with acute phase response, HMGB1 high mobility group box 1, n number of patients