High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins

Table 3 Longitudinal data on disease activity and serum HMGB1 levels in patients with giant cell arteritis

Variables	Baseline (n = 18)	3 months (n = 13)	12 months (n = 6)	Relapse (n = 4)
HMGB1, ng/ml	5.74 ± 4.19	5.18 ± 3.98	8.19 ± 6.80	6.23 ± 2.48
ESR, mm/1^st hour	69.6 ± 28.7	15.1 ± 6.6	21.0 ± 4.9	57.5 ± 24.2
CRP, mg/l	40.0 (20.2–84.2)	2.5 (2.5–7.0)	8.0 (5.1–14.7)	38.5 (12.0–82.2)
Prednisolone, mg/day	--	20.0 (18.7–27.5)	18.7 (3.7–30.0)	6.2 (1.2–9.3)

Continuous variables are presented as median and interquartile range or as mean ± standard deviation
CRP C-reactive protein, ESR erythrocyte sedimentation rate, HMGB1 high mobility group box 1

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