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Table 3 Longitudinal data on disease activity and serum HMGB1 levels in patients with giant cell arteritis

From: High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins

Variables Baseline (n = 18) 3 months (n = 13) 12 months (n = 6) Relapse (n = 4)
HMGB1, ng/ml 5.74 ± 4.19 5.18 ± 3.98 8.19 ± 6.80 6.23 ± 2.48
ESR, mm/1st hour 69.6 ± 28.7 15.1 ± 6.6 21.0 ± 4.9 57.5 ± 24.2
CRP, mg/l 40.0 (20.2–84.2) 2.5 (2.5–7.0) 8.0 (5.1–14.7) 38.5 (12.0–82.2)
Prednisolone, mg/day -- 20.0 (18.7–27.5) 18.7 (3.7–30.0) 6.2 (1.2–9.3)
  1. Continuous variables are presented as median and interquartile range or as mean ± standard deviation
  2. CRP C-reactive protein, ESR erythrocyte sedimentation rate, HMGB1 high mobility group box 1