Fig. 3

Receiver operating characteristic (ROC) curves of sensitivity and specificity of systolic pulmonary arterial pressures (PASP) at rest and at 25 Watts. The threshold for detection of pulmonary hypertension was set at 40 mm Hg for echocardiography at rest and at 45 mm Hg for echocardiography during exercise. All possible thresholds were analysed by ROC analysis for their suitability. The cutoff value for echocardiography during exercise at 45 mm Hg revealed the highest combination of sensitivity and specificity. For the examination at rest, a decrease of the cutoff value would have led to an increase of sensitivity but a crucial decrease of specificity. AUC area under the curve, CI confidence interval