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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter

Fig. 1

SOST mRNA and protein expression levels in normal and osteoarthritis (OA) chondrocytes. a Quantitative SOST mRNA expression in cultured normal (n = 10) and OA chondrocytes (n = 14). GAPDH was used for normalization of the real-time PCR data (error bars = standard error, *p = 0.005). b Representative western blot of SOST protein expression in cultured normal and OA chondrocytes and a bar graph showing relative SOST protein expression normalized to β-actin in normal (n = 5) and OA chondrocytes (n = 5) (error bars = standard error, *p = 0.038)

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Arthritis Research & Therapy

ISSN: 1478-6362

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