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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS

Fig. 1

No increased percentage of hypertrophic chondrocytes expressing Runx2, COL10 or MMP13 within the hyaline articular cartilage in ankylosing spondylitis facet joints. The percentage of positively stained chondrocytes among all chondrocytes [%] and representative immunohistochemical staining of Runx2 (a), COL10 (b), MMP13 (c) and osteocalcin (d) within the hyaline articular cartilage of facet joints from controls (CO; A–D upper pictures), patients with ankylosing spondylitis (AS; A–D middle pictures) and osteoarthritis (OA; A–D lower pictures); original magnification 40× and 400×; ns = not significant p >0.05; ***= p <0.001; **= p <0.01, *= p <0.05. COL10 type X collagen, MMP matrix metalloproteinase, Runx2, runt-related transcription factor 2

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