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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS

Fig. 3

No activation of the wnt pathway in chondrocytes according to beta-catenin staining in ankylosing spondylitis facet joints. Percentage of positively stained chondrocytes [%] and representative immunohistochemical staining of beta-catenin (a), wif-1 (b), DKK-1 (c) and sclerostin (d) in the hyaline articular cartilage of facet joints from controls (CO; A–D upper pictures), patients with ankylosing spondylitis (AS; A–D middle pictures) and osteoarthritis (OA; A–D lower pictures); original magnification 40× and 400×; ns = not significant p >0.05; ***= p <0.001; **= p <0.01. COL10 type X collagen, DKK-1 dickkopf-1, wif-1 wingless inhibitor factor-1, wnt wingless

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