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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS

Fig. 5

Reduced Sox9 expression but increased COL2 expression in ankylosing spondylitis facet joints. Percentage of positively stained chondrocytes among all chondrocytes [%] and representative immunohistochemical staining of Sox9 (a) and COL2 (b) within the hyaline articular cartilage of facet joints from controls (CO; A–B upper pictures), patients with ankylosing spondylitis (AS; A–B middle pictures) and osteoarthritis (OA; A–B lower pictures); original magnification 40× and 400×; ns = not significant p >0.05; ***= p <0.001; *= p <0.05. COL2 type II collagen, Sox9 sex determining region Y (SRY)-box 9

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