TY - JOUR AU - Arbuckle, M. R. AU - McClain, M. T. AU - Rubertone, M. V. AU - Scofield, R. H. AU - Dennis, G. J. AU - James, J. A. PY - 2003 DA - 2003// TI - Development of autoantibodies before the clinical onset of systemic lupus erythematosus JO - N Engl J Med VL - 349 UR - https://doi.org/10.1056/NEJMoa021933 DO - 10.1056/NEJMoa021933 ID - Arbuckle2003 ER - TY - JOUR AU - Sherer, Y. AU - Gorstein, A. AU - Fritzler, M. J. AU - Shoenfeld, Y. PY - 2004 DA - 2004// TI - Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients JO - Semin Arthritis Rheum VL - 34 UR - https://doi.org/10.1016/j.semarthrit.2004.07.002 DO - 10.1016/j.semarthrit.2004.07.002 ID - Sherer2004 ER - TY - JOUR AU - Borg, E. J. AU - Horst, G. AU - Hummel, E. J. AU - Limburg, P. C. AU - Kallenberg, C. G. PY - 1990 DA - 1990// TI - Measurement of increases in anti-double-stranded DNA antibody levels as a predictor of disease exacerbation in systemic lupus erythematosus. A long-term, prospective study JO - Arthritis Rheum VL - 33 UR - https://doi.org/10.1002/art.1780330505 DO - 10.1002/art.1780330505 ID - Borg1990 ER - TY - JOUR AU - Ehrenstein, M. R. AU - Katz, D. R. AU - Griffiths, M. H. AU - Papadaki, L. AU - Winkler, T. H. AU - Kalden, J. R. PY - 1995 DA - 1995// TI - Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice JO - Kidney Int VL - 48 UR - https://doi.org/10.1038/ki.1995.341 DO - 10.1038/ki.1995.341 ID - Ehrenstein1995 ER - TY - JOUR AU - Mina, R. AU - Brunner, H. I. PY - 2010 DA - 2010// TI - Pediatric lupus–are there differences in presentation, genetics, response to therapy, and damage accrual compared with adult lupus? JO - Rheum Dis Clin North Am VL - 36 UR - https://doi.org/10.1016/j.rdc.2009.12.012 DO - 10.1016/j.rdc.2009.12.012 ID - Mina2010 ER - TY - JOUR AU - Brunner, H. I. AU - Gladman, D. D. AU - Ibañez, D. AU - Urowitz, M. D. AU - Silverman, E. D. PY - 2008 DA - 2008// TI - Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus JO - Arthritis Rheum VL - 58 UR - https://doi.org/10.1002/art.23204 DO - 10.1002/art.23204 ID - Brunner2008 ER - TY - JOUR AU - Tucker, L. B. AU - Uribe, A. G. AU - Fernández, M. AU - Vilá, L. M. AU - McGwin, G. AU - Apte, M. PY - 2008 DA - 2008// TI - Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case–control study within LUMINA, a multiethnic US cohort (LUMINA LVII) JO - Lupus VL - 17 UR - https://doi.org/10.1177/0961203307087875 DO - 10.1177/0961203307087875 ID - Tucker2008 ER - TY - JOUR AU - Hagelberg, S. AU - Lee, Y. AU - Bargman, J. AU - Mah, G. AU - Schneider, R. AU - Laskin, C. PY - 2002 DA - 2002// TI - Longterm followup of childhood lupus nephritis JO - J Rheumatol VL - 29 ID - Hagelberg2002 ER - TY - JOUR AU - Bennett, M. AU - Brunner, H. I. PY - 2013 DA - 2013// TI - Biomarkers and updates on pediatrics lupus nephritis JO - Rheum Dis Clin North Am VL - 39 UR - https://doi.org/10.1016/j.rdc.2013.05.001 DO - 10.1016/j.rdc.2013.05.001 ID - Bennett2013 ER - TY - JOUR AU - Gilliam, B. E. AU - Ombrello, A. K. AU - Burlingame, R. W. AU - Pepmueller, P. H. AU - Moore, T. L. PY - 2012 DA - 2012// TI - Measurement of autoantibodies in pediatric-onset systemic lupus erythematosus and their relationship with disease-associated manifestations JO - Semin Arthritis Rheum VL - 41 UR - https://doi.org/10.1016/j.semarthrit.2011.09.009 DO - 10.1016/j.semarthrit.2011.09.009 ID - Gilliam2012 ER - TY - JOUR AU - Marks, S. D. AU - Williams, S. J. AU - Tullus, K. AU - Sebire, N. J. PY - 2008 DA - 2008// TI - Glomerular expression of monocyte chemoattractant protein-1 is predictive of poor renal prognosis in pediatric lupus nephritis JO - Nephrol Dial Transplant VL - 23 UR - https://doi.org/10.1093/ndt/gfn270 DO - 10.1093/ndt/gfn270 ID - Marks2008 ER - TY - JOUR AU - Chan, R. W. AU - Tam, L. S. AU - Li, E. K. AU - Lai, F. M. AU - Chow, K. M. AU - Lai, K. B. PY - 2003 DA - 2003// TI - Inflammatory cytokine gene expression in the urinary sediment of patients with lupus nephritis JO - Arthritis Rheum VL - 48 UR - https://doi.org/10.1002/art.11062 DO - 10.1002/art.11062 ID - Chan2003 ER - TY - JOUR AU - Fu, Q. AU - Chen, X. AU - Cui, H. AU - Guo, Y. AU - Chen, J. AU - Shen, N. PY - 2008 DA - 2008// TI - Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients JO - Arthritis Res Ther VL - 10 UR - https://doi.org/10.1186/ar2510 DO - 10.1186/ar2510 ID - Fu2008 ER - TY - JOUR AU - Suzuki, M. AU - Ross, G. F. AU - Wiers, K. AU - Nelson, S. AU - Bennett, M. AU - Passo, M. H. PY - 2007 DA - 2007// TI - Identification of a urinary proteomic signature for lupus nephritis in children JO - Pediatr Nephrol VL - 22 UR - https://doi.org/10.1007/s00467-007-0608-x DO - 10.1007/s00467-007-0608-x ID - Suzuki2007 ER - TY - JOUR AU - Brunner, H. I. AU - Bennett, M. R. AU - Mina, R. AU - Suzuki, M. AU - Petri, M. AU - Kiani, A. N. PY - 2012 DA - 2012// TI - Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritis JO - Arthritis Rheum VL - 64 UR - https://doi.org/10.1002/art.34426 DO - 10.1002/art.34426 ID - Brunner2012 ER - TY - JOUR AU - Rovin, B. H. AU - Birmingham, D. J. AU - Nagaraja, H. N. AU - Yu, C. Y. AU - Hebert, L. A. PY - 2007 DA - 2007// TI - Biomarker discovery in human SLE nephritis JO - Bull NYU Hosp Jt Dis VL - 65 ID - Rovin2007 ER - TY - JOUR AU - Pickering, M. C. AU - Botto, M. AU - Taylor, P. R. AU - Lachmann, P. J. AU - Walport, M. J. PY - 2000 DA - 2000// TI - Systemic lupus erythematosus, complement deficiency, and apoptosis JO - Adv Immunol VL - 76 UR - https://doi.org/10.1016/S0065-2776(01)76021-X DO - 10.1016/S0065-2776(01)76021-X ID - Pickering2000 ER - TY - JOUR AU - Robinson, W. H. AU - DiGennaro, C. AU - Hueber, W. AU - Haab, B. B. AU - Kamachi, M. AU - Dean, E. J. PY - 2002 DA - 2002// TI - Autoantigen microarrays for multiplex characterization of autoantibody responses JO - Nat Med VL - 8 UR - https://doi.org/10.1038/nm0302-295 DO - 10.1038/nm0302-295 ID - Robinson2002 ER - TY - JOUR AU - Balboni, I. AU - Niewold, T. B. AU - Morgan, G. AU - Limb, C. AU - Eloranta, M. L. AU - Rönnblom, L. PY - 2013 DA - 2013// TI - Interferon-α induction and detection of anti-ro, anti-la, anti-sm, and anti-rnp autoantibodies by autoantigen microarray analysis in juvenile dermatomyositis JO - Arthritis Rheum VL - 65 UR - https://doi.org/10.1002/art.38038 DO - 10.1002/art.38038 ID - Balboni2013 ER - TY - JOUR AU - Price, J. V. AU - Haddon, D. J. AU - Kemmer, D. AU - Delepine, G. AU - Mandelbaum, G. AU - Jarrell, J. A. PY - 2013 DA - 2013// TI - Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus JO - J Clin Invest VL - 123 UR - https://doi.org/10.1172/JCI70231 DO - 10.1172/JCI70231 ID - Price2013 ER - TY - JOUR AU - Price, J. V. AU - Tangsombatvisit, S. AU - Xu, G. AU - Yu, J. AU - Levy, D. AU - Baechler, E. C. PY - 2012 DA - 2012// TI - On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions JO - Nat Med VL - 18 UR - https://doi.org/10.1038/nm.2913 DO - 10.1038/nm.2913 ID - Price2012 ER - TY - JOUR AU - Baechler, E. C. AU - Batliwalla, F. M. AU - Karypis, G. AU - Gaffney, P. M. AU - Ortmann, W. A. AU - Espe, K. J. PY - 2003 DA - 2003// TI - Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus JO - Proc Natl Acad Sci U S A VL - 100 UR - https://doi.org/10.1073/pnas.0337679100 DO - 10.1073/pnas.0337679100 ID - Baechler2003 ER - TY - JOUR AU - Bauer, J. W. AU - Petri, M. AU - Batliwalla, F. M. AU - Koeuth, T. AU - Wilson, J. AU - Slattery, C. PY - 2009 DA - 2009// TI - Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study JO - Arthritis Rheum VL - 60 UR - https://doi.org/10.1002/art.24803 DO - 10.1002/art.24803 ID - Bauer2009 ER - TY - JOUR AU - Bennett, L. AU - Palucka, A. K. AU - Arce, E. AU - Cantrell, V. AU - Borvak, J. AU - Banchereau, J. PY - 2003 DA - 2003// TI - Interferon and granulopoiesis signatures in systemic lupus erythematosus blood JO - J Exp Med VL - 197 UR - https://doi.org/10.1084/jem.20021553 DO - 10.1084/jem.20021553 ID - Bennett2003 ER - TY - JOUR AU - Bauer, J. W. AU - Baechler, E. C. AU - Petri, M. AU - Batliwalla, F. M. AU - Crawford, D. AU - Ortmann, W. A. PY - 2006 DA - 2006// TI - Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus JO - PLoS Med VL - 3 UR - https://doi.org/10.1371/journal.pmed.0030491 DO - 10.1371/journal.pmed.0030491 ID - Bauer2006 ER - TY - JOUR AU - Hochberg, M. C. PY - 1997 DA - 1997// TI - Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus JO - Arthritis Rheum VL - 40 UR - https://doi.org/10.1002/art.1780400928 DO - 10.1002/art.1780400928 ID - Hochberg1997 ER - TY - JOUR AU - Weening, J. J. AU - D'Agati, V. D. AU - Schwartz, M. M. AU - Seshan, S. V. AU - Alpers, C. E. AU - Appel, G. B. PY - 2004 DA - 2004// TI - The classification of glomerulonephritis in systemic lupus erythematosus revisited JO - J Am Soc Nephrol VL - 15 UR - https://doi.org/10.1097/01.ASN.0000108969.21691.5D DO - 10.1097/01.ASN.0000108969.21691.5D ID - Weening2004 ER - TY - JOUR AU - Balboni, I. AU - Chan, S. M. AU - Kattah, M. AU - Tenenbaum, J. D. AU - Butte, A. J. AU - Utz, P. J. PY - 2006 DA - 2006// TI - Multiplexed protein array platforms for analysis of autoimmune diseases JO - Annu Rev Immunol VL - 24 UR - https://doi.org/10.1146/annurev.immunol.24.021605.090709 DO - 10.1146/annurev.immunol.24.021605.090709 ID - Balboni2006 ER - TY - JOUR AU - Edgar, R. AU - Domrachev, M. AU - Lash, A. E. PY - 2002 DA - 2002// TI - Gene Expression Omnibus: NCBI gene expression and hybridization array data repository JO - Nucleic Acids Res VL - 30 UR - https://doi.org/10.1093/nar/30.1.207 DO - 10.1093/nar/30.1.207 ID - Edgar2002 ER - TY - STD TI - Autoantigen microarray data series on GEO. http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE69662. UR - http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE69662 ID - ref30 ER - TY - JOUR AU - Tusher, V. G. AU - Tibshirani, R. AU - Chu, G. PY - 2001 DA - 2001// TI - Significance analysis of microarrays applied to the ionizing radiation response JO - Proc Natl Acad Sci U S A VL - 98 UR - https://doi.org/10.1073/pnas.091062498 DO - 10.1073/pnas.091062498 ID - Tusher2001 ER - TY - STD TI - R Core Team. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing; 2013. ID - ref32 ER - TY - BOOK AU - Tibshirani, R. AU - Chu, G. AU - Narasimhan, B. AU - Li, J. PY - 2011 DA - 2011// TI - samr: SAM: significance analysis of microarrays. 20th ed PB - R package CY - Stanford ID - Tibshirani2011 ER - TY - BOOK AU - Warnes, G. R. AU - Bolker, B. AU - Bonebakker, L. AU - Gentleman, R. AU - Huber, W. AU - Liaw, A. PY - 2013 DA - 2013// TI - gplots: various R programming tools for plotting data. 3th ed PB - New Milford CY - R package ID - Warnes2013 ER - TY - STD TI - Tibshirani R. Regression shrinkage and selection via the lasso. J R Stat Soc Ser B. 1996;267–288. ID - ref35 ER - TY - JOUR AU - Friedman, J. AU - Hastie, T. AU - Tibshirani, R. PY - 2010 DA - 2010// TI - Regularization paths for generalized linear models via coordinate descent JO - J Stat Softw VL - 33 ID - Friedman2010 ER - TY - JOUR AU - Trendelenburg, M. AU - Lopez-Trascasa, M. AU - Potlukova, E. AU - Moll, S. AU - Regenass, S. AU - Frémeaux-Bacchi, V. PY - 2006 DA - 2006// TI - High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis JO - Nephrol Dial Transplant VL - 21 UR - https://doi.org/10.1093/ndt/gfl436 DO - 10.1093/ndt/gfl436 ID - Trendelenburg2006 ER - TY - JOUR AU - Mahler, M. AU - Schaarenburg, R. A. AU - Trouw, L. A. PY - 2013 DA - 2013// TI - Anti-C1q autoantibodies, novel tests, and clinical consequences JO - Front Immunol VL - 4 UR - https://doi.org/10.3389/fimmu.2013.00117 DO - 10.3389/fimmu.2013.00117 ID - Mahler2013 ER - TY - JOUR AU - Renaudineau, Y. AU - Croquefer, S. AU - Jousse, S. AU - Renaudineau, E. AU - Devauchelle, V. AU - Guéguen, P. PY - 2006 DA - 2006// TI - Association of alpha-actinin-binding anti-double-stranded DNA antibodies with lupus nephritis JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.22015 DO - 10.1002/art.22015 ID - Renaudineau2006 ER - TY - JOUR AU - McIntosh, R. M. AU - Kaufman, D. B. AU - Griswold, W. AU - Smith, F. G. AU - Vernier, R. L. PY - 1971 DA - 1971// TI - Glomerular localization of ibrinogen–clinicopathologic, prognostic and therapeutic considerations JO - J Chronic Dis VL - 24 UR - https://doi.org/10.1016/0021-9681(71)90089-0 DO - 10.1016/0021-9681(71)90089-0 ID - McIntosh1971 ER - TY - JOUR AU - Nagayama, Y. AU - Imura, H. AU - Muso, R. PY - 1992 DA - 1992// TI - Decrease in renal function following decreased fibrinogen and raised fibrin degradation products in lupus nephritis with nephrotic syndrome JO - Scand J Urol Nephrol VL - 26 UR - https://doi.org/10.3109/00365599209181231 DO - 10.3109/00365599209181231 ID - Nagayama1992 ER - TY - JOUR AU - Navarra, S. V. AU - Guzmán, R. M. AU - Gallacher, A. E. AU - Hall, S. AU - Levy, R. A. AU - Jimenez, R. E. PY - 2011 DA - 2011// TI - Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial JO - Lancet VL - 377 UR - https://doi.org/10.1016/S0140-6736(10)61354-2 DO - 10.1016/S0140-6736(10)61354-2 ID - Navarra2011 ER - TY - JOUR AU - Li, P. H. AU - Wong, W. H. AU - Lee, T. L. AU - Lau, C. S. AU - Chan, T. M. AU - Leung, A. M. PY - 2013 DA - 2013// TI - Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese JO - Rheumatology (Oxford) VL - 52 UR - https://doi.org/10.1093/rheumatology/kes261 DO - 10.1093/rheumatology/kes261 ID - Li2013 ER - TY - JOUR AU - Hoffman, I. E. AU - Peene, I. AU - Meheus, L. AU - Huizinga, T. W. AU - Cebecauer, L. AU - Isenberg, D. PY - 2004 DA - 2004// TI - Specific antinuclear antibodies are associated with clinical features in systemic lupus erythematosus JO - Ann Rheum Dis VL - 63 UR - https://doi.org/10.1136/ard.2003.013417 DO - 10.1136/ard.2003.013417 ID - Hoffman2004 ER - TY - JOUR AU - Jurencák, R. AU - Fritzler, M. AU - Tyrrell, P. AU - Hiraki, L. AU - Benseler, S. AU - Silverman, E. PY - 2009 DA - 2009// TI - Autoantibodies in pediatric systemic lupus erythematosus: ethnic grouping, cluster analysis, and clinical correlations JO - J Rheumatol VL - 36 UR - https://doi.org/10.3899/jrheum.080588 DO - 10.3899/jrheum.080588 ID - Jurencák2009 ER - TY - JOUR AU - Levy, D. M. AU - Peschken, C. A. AU - Tucker, L. B. AU - Chédeville, G. AU - Huber, A. M. AU - Pope, J. E. PY - 2013 DA - 2013// TI - Influence of ethnicity on childhood-onset systemic lupus erythematosus: results from a multiethnic multicenter Canadian cohort JO - Arthritis Care Res (Hoboken) VL - 65 UR - https://doi.org/10.1002/acr.21779 DO - 10.1002/acr.21779 ID - Levy2013 ER - TY - JOUR AU - Ravelli, A. AU - Wisnieski, J. J. AU - Ramenghi, B. AU - Ballardini, G. AU - Zonta, L. AU - Martini, A. PY - 1997 DA - 1997// TI - IgG autoantibodies to complement C1q in pediatric-onset systemic lupus erythematosus JO - Clin Exp Rheumatol VL - 15 ID - Ravelli1997 ER - TY - JOUR AU - Kozyro, I. AU - Perahud, I. AU - Sadallah, S. AU - Sukalo, A. AU - Titov, L. AU - Schifferli, J. PY - 2006 DA - 2006// TI - Clinical value of autoantibodies against C1q in children with glomerulonephritis JO - Pediatrics VL - 117 UR - https://doi.org/10.1542/peds.2005-1148 DO - 10.1542/peds.2005-1148 ID - Kozyro2006 ER - TY - JOUR AU - Wu, F. Q. AU - Zhao, Q. AU - Cui, X. D. AU - Zhang, W. PY - 2011 DA - 2011// TI - C1q and anti-C1q antibody levels are correlated with disease severity in Chinese pediatric systemic lupus erythematosus JO - Rheumatol Int VL - 31 UR - https://doi.org/10.1007/s00296-009-1257-0 DO - 10.1007/s00296-009-1257-0 ID - Wu2011 ER - TY - JOUR AU - Vynios, D. H. AU - Tsagaraki, I. AU - Grigoreas, G. H. AU - Samiotaki, M. AU - Panayotou, G. AU - Kyriakopoulou, D. PY - 2006 DA - 2006// TI - Autoantibodies against aggrecan in systemic rheumatic diseases JO - Biochimie VL - 88 UR - https://doi.org/10.1016/j.biochi.2006.01.004 DO - 10.1016/j.biochi.2006.01.004 ID - Vynios2006 ER - TY - JOUR AU - Li, Q. Z. AU - Zhen, Q. L. AU - Xie, C. AU - Wu, T. AU - Mackay, M. AU - Aranow, C. PY - 2005 DA - 2005// TI - Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays JO - J Clin Invest VL - 115 UR - https://doi.org/10.1172/JCI23587 DO - 10.1172/JCI23587 ID - Li2005 ER - TY - JOUR AU - Quintana, F. J. AU - Getz, G. AU - Hed, G. AU - Domany, E. AU - Cohen, I. R. PY - 2003 DA - 2003// TI - Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity JO - J Autoimmun VL - 21 UR - https://doi.org/10.1016/S0896-8411(03)00064-7 DO - 10.1016/S0896-8411(03)00064-7 ID - Quintana2003 ER -